Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | HK1 | P19367 | 1/20 | 0.53 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MGAM | O43451 | 1/20 | 0.48 |
| ▸ | SI | P14410 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7988824 | 0.99 | MAPT (0.54) | MAPTMEN1KMT2AGAAMAPK1 | |
| SCHEMBL7989590 | 0.95 | MAPT (0.53) | MAPTMEN1KMT2AGAAMAPK1 | |
| Hydrochloric Acid SCHEMBL7977698 | 0.94 | MAPT (0.53) | MAPTMEN1KMT2AGAAMAPK1 | |
| SCHEMBL7995159 | 0.93 | MAPT (0.56) | MAPTMEN1KMT2AGAAMAPK1 | |
| Hydrochloric Acid SCHEMBL7991995 | 0.92 | MAPT (0.56) | MAPTMEN1KMT2AGAAMAPK1 | |
| SCHEMBL7988575 | 0.91 | ADORA2A (0.58) | MAPTMEN1KMT2AGAAMAPK1 | |
| SCHEMBL7989593 | 0.88 | MEN1 (0.56) | MAPTMEN1KMT2AGAAMAPK1 | |
| SCHEMBL7992126 | 0.88 | NPC1 (0.46) | MAPTMEN1KMT2AGAAMAPK1 | |
| SCHEMBL7977611 | 0.87 | MAPK1 (0.49) | MAPTMEN1KMT2AGAAMAPK1 | |
| Hydrochloric Acid SCHEMBL7987780 | 0.86 | MEN1 (0.55) | MAPTMEN1KMT2AGAAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288061-B1 | INTERLEUKIN INHIBITORS; ASTHMA, BRONCHODILATOR AGENTS, ANTIALLERGENS | WELFIDE CORPORATION (JP) | 2001-09-11 | — | — | US | disclosed |