Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.44 |
| ▸ | HK1 | P19367 | 1/20 | 0.44 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7989961 | 0.94 | MAPK1 (0.45) | MAPK1L3MBTL1MEN1KMT2AMAPT | |
| SCHEMBL7989590 | 0.92 | MAPT (0.53) | MAPK1L3MBTL1MEN1KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL7977698 | 0.91 | MAPT (0.53) | MAPK1L3MBTL1MEN1KMT2AMAPT | |
| SCHEMBL7987889 | 0.90 | MAPK1 (0.52) | MAPK1L3MBTL1MEN1KMT2AMAPT | |
| SCHEMBL7977760 | 0.88 | MAPK1 (0.51) | MAPK1L3MBTL1MEN1KMT2AMAPT | |
| SCHEMBL7992126 | 0.87 | NPC1 (0.46) | MAPK1L3MBTL1MEN1KMT2AMAPT | |
| SCHEMBL7992215 | 0.87 | MAPT (0.55) | MAPK1L3MBTL1MEN1KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL7988824 | 0.86 | MAPT (0.54) | MAPK1L3MBTL1MEN1KMT2AMAPT | |
| SCHEMBL7988807 | 0.86 | ADORA2A (0.45) | MAPK1L3MBTL1MEN1KMT2AMAPT | |
| SCHEMBL7992383 | 0.86 | L3MBTL1 (0.51) | MAPK1L3MBTL1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288061-B1 | INTERLEUKIN INHIBITORS; ASTHMA, BRONCHODILATOR AGENTS, ANTIALLERGENS | WELFIDE CORPORATION (JP) | 2001-09-11 | — | — | US | disclosed |