Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
| ▸ | SI | P14410 | 1/20 | 0.35 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25482221 | 0.87 | NFE2L2 (0.39) | KDM4ENFE2L2KCNH2PDGFRBPDGFRA | |
| SCHEMBL765434 | 0.86 | GAA (0.43) | KDM4ENFE2L2KCNH2PDGFRBPDGFRA | |
| SCHEMBL12563123 | 0.84 | KDM4E (0.39) | KDM4ENFE2L2KCNH2PDGFRBPDGFRA | |
| SCHEMBL30166162 | 0.82 | CYP2D6 (0.41) | KDM4E | |
| SCHEMBL3725877 | 0.82 | CYP2D6 (0.41) | KDM4E | |
| SCHEMBL31280158 | 0.82 | MGAM (0.42) | KDM4ENFE2L2KCNH2PDGFRBPDGFRA | |
| SCHEMBL25408937 | 0.82 | KDM4E (0.38) | KDM4ENFE2L2KCNH2PDGFRBPDGFRA | |
| SCHEMBL25180793 | 0.82 | CYP2D6 (0.41) | KDM4E | |
| SCHEMBL30949362 | 0.82 | CYP2D6 (0.41) | KDM4E | |
| SCHEMBL12563119 | 0.82 | MGAM (0.42) | KDM4ENFE2L2KCNH2GAAMGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6277851-B1 | ORALLY ADMINISTERED TRYPSIN-RELATED SERINE PROTEASE INHIBITORS; ANTICOAGULANTS | ADIR ET COMPAGNIE (FR) | 2001-08-21 | — | — | US | disclosed |