Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 10/20 | 0.58 |
| ▸ | PIK3CA | P42336 | 10/20 | 0.58 |
| ▸ | PIK3CG | P48736 | 10/20 | 0.58 |
| ▸ | PIK3CB | P42338 | 8/20 | 0.58 |
| ▸ | PI4KB | Q9UBF8 | 9/20 | 0.51 |
| ▸ | CLK1 | P49759 | 1/20 | 0.51 |
| ▸ | CLK2 | P49760 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL799251 | 0.82 | PIK3CD (0.62) | PIK3CDPIK3CAPIK3CGPIK3CBPI4KB | |
| SCHEMBL48530 | 0.77 | PIK3CD (0.65) | PIK3CDPIK3CAPIK3CGPIK3CBPI4KB | |
| SCHEMBL12363422 | 0.77 | PIK3CD (0.80) | PIK3CDPIK3CAPIK3CGPIK3CBPI4KB | |
| SCHEMBL1784923 | 0.77 | PIK3CD (0.70) | PIK3CDPIK3CAPIK3CGPIK3CBPI4KB | |
| SCHEMBL5785803 | 0.77 | PIK3CG (0.70) | PIK3CDPIK3CAPIK3CGPIK3CBPI4KB | |
| SCHEMBL27658350 | 0.77 | PIK3CD (0.70) | PIK3CDPIK3CAPIK3CGPIK3CBPI4KB | |
| SCHEMBL48455 | 0.76 | PIK3CD (0.75) | PIK3CDPIK3CAPIK3CGPIK3CBPI4KB | |
| SCHEMBL1784085 | 0.76 | PIK3CG (0.68) | PIK3CDPIK3CAPIK3CGPIK3CBPI4KB | |
| SCHEMBL1786524 | 0.76 | PIK3CG (0.75) | PIK3CDPIK3CAPIK3CGPIK3CBPI4KB | |
| SCHEMBL1784080 | 0.76 | PIK3CG (0.68) | PIK3CDPIK3CAPIK3CGPIK3CBPI4KB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120071475-A1 | UREA DERIVATIVES HAVING PI3K-INHIBITING ACTIVITY | SHIONOGI & CO., LTD. (JP) | 2012-03-22 | — | — | US | disclosed |
| US-20120071475-A1 | UREA DERIVATIVES HAVING PI3K-INHIBITING ACTIVITY | SHIONOGI & CO., LTD. (JP) | 2012-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120071475-A1 | UREA DERIVATIVES HAVING PI3K-INHIBITING ACTIVITY | MTOR, STAT3, SLC14A1 | PIK3CD 10/4885PIK3CA 15/4885PIK3CG 16/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.