Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 9/20 | 0.78 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | DRD2 | P14416 | 6/20 | 0.54 |
| ▸ | DRD3 | P35462 | 6/20 | 0.54 |
| ▸ | DRD4 | P21917 | 5/20 | 0.54 |
| ▸ | OPRM1 | P35372 | 8/20 | 0.53 |
| ▸ | OPRD1 | P41143 | 8/20 | 0.53 |
| ▸ | OPRK1 | P41145 | 8/20 | 0.53 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.52 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7754117 | 0.92 | OPRL1 (0.81) | OPRL1MEN1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL29766745 | 0.88 | OPRL1 (1.00) | OPRL1MEN1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL7757872 | 0.88 | OPRL1 (1.00) | OPRL1MEN1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL7992795 | 0.87 | OPRL1 (0.76) | OPRL1MEN1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL7754142 | 0.86 | OPRL1 (0.74) | OPRL1MEN1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL7754138 | 0.85 | OPRL1 (0.72) | OPRL1MEN1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL7754144 | 0.85 | OPRL1 (0.72) | OPRL1MEN1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL5108205 | 0.85 | OPRL1 (0.72) | OPRL1MEN1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL7999928 | 0.84 | OPRL1 (0.67) | OPRL1DRD2DRD3DRD4OPRM1 | |
| Hydrochloric Acid SCHEMBL7758893 | 0.84 | OPRL1 (0.71) | OPRL1MEN1CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001036418-A1 | NOVEL TRIAZASPIRODECANONES WITH HIGH AFFINITY FOR OPIOID RECEPTOR SUBTYPES | NOVO NORDISK A/S (DK) | 2001-05-25 | — | — | WO | disclosed |