Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6060213 | 0.80 | ALDH1A1 (0.36) | LMNAALDH1A1SMN1; SMN2CYP2C19TSHR | |
| SCHEMBL14411500 | 0.78 | ALDH1A1 (0.33) | LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL6059815 | 0.75 | — | — | |
| SCHEMBL13327624 | 0.75 | — | — | |
| SCHEMBL16904971 | 0.75 | — | — | |
| SCHEMBL19958880 | 0.71 | SMN1; SMN2 (0.37) | LMNAALDH1A1SMN1; SMN2CYP2C9CYP2C19 | |
| SCHEMBL11404630 | 0.70 | ALDH1A1 (0.37) | LMNAALDH1A1CYP2C9 | |
| SCHEMBL11405101 | 0.69 | ALDH1A1 (0.36) | LMNAALDH1A1CYP2C9 | |
| SCHEMBL13776582 | 0.67 | CYP2C9 (0.34) | LMNAALDH1A1SMN1; SMN2CYP2C9CYP2C19 | |
| SCHEMBL24780441 | 0.67 | SMN1; SMN2 (0.33) | LMNAALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6258963-B1 | DRUGS, COSMETICS | HAARMANN & REIMER GMBH (DE) | 2001-07-10 | — | — | US | disclosed |
| EP-1008593-A1 | Benzylidene-gamma-butyrolactones, process for their production and use thereof as UV absorbers | HAARMANN & REIMER GMBH (DE) | 2000-06-14 | — | — | EP | disclosed |