SCHEMBL7992897

CC(C)(C)OC(=O)N=C(c1ccc(C(=O)N[C@@H](Cc2ccc(C#N)cc2)C(=O)N2CCc3nn(CC(=O)O)cc3C2)cc1)N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C

nearest known ligand 0.52

Predicted protein targets (top 8)

	gene	UniProt	supporting neighbours	confidence
▸	ITGB3	P05106	1/20	0.52

▸	ITGA2B	P08514	1/20	0.52

▸	FPR1	P21462	12/20	0.39

▸	FPR2	P25090	12/20	0.39

▸	KMT2A	Q03164	1/20	0.38

▸	HCRTR2	O43614	2/20	0.37

▸	P2RX7	Q99572	1/20	0.37

▸	KDM1A	O60341	1/20	0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL7988232	0.93	ITGB3 (0.45)	ITGB3ITGA2BFPR1FPR2KMT2A
SCHEMBL7992487	0.92	ITGB3 (0.54)	ITGB3ITGA2BKMT2AHCRTR2
SCHEMBL7992489	0.92	ITGB3 (0.54)	ITGB3ITGA2BKMT2AHCRTR2
SCHEMBL7975369	0.92	ITGB3 (0.54)	ITGB3ITGA2BKMT2AHCRTR2P2RX7
SCHEMBL7987066	0.92	ITGB3 (0.54)	ITGB3ITGA2BFPR1FPR2KMT2A
SCHEMBL7989496	0.90	ITGB3 (0.51)	ITGB3ITGA2BKMT2AHCRTR2P2RX7
SCHEMBL7992289	0.89	ITGB3 (0.67)	ITGB3ITGA2BKMT2AHCRTR2P2RX7
SCHEMBL7974819	0.88	ITGB3 (0.48)	ITGB3ITGA2BKMT2AHCRTR2
SCHEMBL7974821	0.88	ITGB3 (0.48)	ITGB3ITGA2BKMT2AHCRTR2
SCHEMBL7992560	0.86	ITGB3 (0.45)	ITGB3ITGA2BKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-6265418-B1	ANTICOAGULANTS	UBE INDUSTRIES, LTD. (JP)	2001-07-24	—	—	US	disclosed
EP-1020467-A1	N-ACYLAMINO ACID AMIDE COMPOUNDS AND INTERMEDIATES FOR PREPARATION THEREOF	UBE INDUSTRIES LIMITED (JP)	2000-07-19	—	—	EP	disclosed