Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.57 |
| ▸ | CTSS | P25774 | 1/20 | 0.54 |
| ▸ | PPARG | P37231 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KLK7 | P49862 | 2/20 | 0.47 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7992987 | 1.00 | PPARA (0.57) | PPARACTSSPPARGRAB9AKLK7 | |
| SCHEMBL1341914 | 0.83 | PPARA (0.57) | PPARACTSSPPARGRAB9AKLK7 | |
| SCHEMBL1343633 | 0.83 | PPARA (0.57) | PPARACTSSPPARGRAB9AKLK7 | |
| SCHEMBL7989516 | 0.83 | MMP3 (0.42) | — | |
| SCHEMBL9439194 | 0.79 | PPARA (0.62) | PPARACTSSPPARGRAB9AKLK7 | |
| SCHEMBL30836085 | 0.79 | PPARA (0.67) | PPARACTSSPPARGRAB9AKLK7 | |
| SCHEMBL7987678 | 0.79 | SLC1A1 (0.43) | L3MBTL1 | |
| SCHEMBL7987674 | 0.79 | SLC1A1 (0.43) | L3MBTL1 | |
| SCHEMBL2897805 | 0.79 | PPARA (0.67) | PPARACTSSPPARGRAB9AKLK7 | |
| SCHEMBL2897802 | 0.79 | PPARA (0.67) | PPARACTSSPPARGRAB9AKLK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001040198-A2 | MACROCYCLIC HYDROXAMIC ACID DERIVATIVES AND THEIR USE AS ANTIMICROBIAL AGENTS | AVENTIS PHARMA S.A. (FR) | 2001-06-07 | — | — | WO | disclosed |