Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.76 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.76 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.76 |
| ▸ | MEN1 | O00255 | 3/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.76 |
| ▸ | PGR | P06401 | 3/20 | 0.76 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.76 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.76 |
| ▸ | MAPT | P10636 | 2/20 | 0.76 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.76 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.76 |
| ▸ | HPGD | P15428 | 1/20 | 0.76 |
| ▸ | MLNR | O43193 | 1/20 | 0.76 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.76 |
| ▸ | HTT | P42858 | 1/20 | 0.76 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.76 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.76 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.76 |
| ▸ | AR | P10275 | 2/20 | 0.61 |
| ▸ | SHBG | P04278 | 4/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15756108 | 0.90 | AR (0.73) | LMNANR3C1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL3940460 | 0.89 | LMNA (0.73) | LMNANR3C1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL4971448 | 0.89 | LMNA (0.73) | LMNANR3C1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL14656870 | 0.87 | LMNA (0.98) | LMNANR3C1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL5425550 | 0.87 | LMNA (0.98) | LMNANR3C1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL353516 | 0.87 | LMNA (0.98) | LMNANR3C1SMN1; SMN2MEN1KMT2A | |
| Hydroxyprogesterone Caproate SCHEMBL94788 | 0.86 | LMNA (1.00) | LMNANR3C1SMN1; SMN2MEN1KMT2A | |
| Hydroxyprogesterone Caproate SCHEMBL508890 | 0.86 | LMNA (1.00) | LMNANR3C1SMN1; SMN2MEN1KMT2A | |
| Hydroxyprogesterone Caproate SCHEMBL17517045 | 0.86 | LMNA (1.00) | LMNANR3C1SMN1; SMN2MEN1KMT2A | |
| Hydroxyprogesterone Caproate SCHEMBL5330 | 0.86 | LMNA (1.00) | LMNANR3C1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6274118-B1 | INJECTING PATIENT HAVING ENDOCRINE CANCER IN NON-PROSTATIC TISSUE WITH BIOLOGICAL BINDING UNITS WHICH BIND TO PROSTATE SPECIFIC ANTIGEN PRODUCED BY NON-PROSTATIC TISSUE | NORDION INTERNATIONAL INC. (CA) | 2001-08-14 | — | — | US | disclosed |
| WO-1995002424-A1 | LOCALIZATION AND THERAPY OF NON-PROSTATIC ENDOCRINE CANCER WITH AGENTS DIRECTED AGAINST PROSTATE SPECIFIC ANTIGEN | NORDION INTERNATIONAL INC. (CA) | 1995-01-26 | — | — | WO | disclosed |