Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 10/20 | 0.55 |
| ▸ | FNTB | P49356 | 10/20 | 0.55 |
| ▸ | PGGT1B | P53609 | 7/20 | 0.55 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7993202 | 1.00 | FNTA (0.55) | FNTAFNTBPGGT1BKDM1AMAOA | |
| Hydrochloric Acid SCHEMBL8000784 | 0.99 | FNTA (0.54) | FNTAFNTBPGGT1BKDM1AMAOA | |
| Hydrochloric Acid SCHEMBL8000780 | 0.99 | FNTA (0.54) | FNTAFNTBPGGT1BKDM1AMAOA | |
| SCHEMBL8934738 | 0.87 | FNTA (0.44) | FNTAFNTBPGGT1B | |
| SCHEMBL8934741 | 0.87 | FNTA (0.44) | FNTAFNTBPGGT1B | |
| SCHEMBL7983219 | 0.81 | FNTA (0.60) | FNTAFNTBPGGT1B | |
| SCHEMBL7983222 | 0.81 | FNTA (0.60) | FNTAFNTBPGGT1B | |
| SCHEMBL7994795 | 0.79 | FNTA (0.58) | FNTAFNTBPGGT1B | |
| SCHEMBL7994798 | 0.79 | FNTA (0.58) | FNTAFNTBPGGT1B | |
| SCHEMBL9518079 | 0.79 | AKR1C3 (0.51) | KDM1AMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0817629-A4 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO INC (US) | 2000-03-08 | — | — | EP | claimed |
| EP-0817629-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | Merck & Co., Inc. (US) | 1998-01-14 | — | — | EP | claimed |
| EP-0817629-A4 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO INC (US) | 2000-03-08 | — | — | EP | disclosed |
| EP-0817629-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | Merck & Co., Inc. (US) | 1998-01-14 | — | — | EP | disclosed |
| US-5631280-A | Inhibitors of farnesyl-protein transferase | MERCK & CO., INC. (US) | 1997-05-20 | — | — | US | disclosed |
| WO-1996030014-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1996-10-03 | — | — | WO | disclosed |