Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | KDM1A | O60341 | 2/20 | 0.49 |
| ▸ | MAOA | P21397 | 2/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.46 |
| ▸ | PLAU | P00749 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.45 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8000780 | 0.80 | FNTA (0.54) | KDM1AMAOAMAOB | |
| Hydrochloric Acid SCHEMBL8000784 | 0.80 | FNTA (0.54) | KDM1AMAOAMAOB | |
| SCHEMBL9368758 | 0.80 | HTT (0.73) | HTTKDM1AMAOAMAOBKMT2A | |
| SCHEMBL9001650 | 0.80 | MAOA (0.63) | HTTKDM1AMAOAMAOBKMT2A | |
| SCHEMBL1039232 | 0.79 | ALDH1A1 (0.54) | AKR1C3KDM1AKMT2ATSHRL3MBTL1 | |
| Hydrochloric Acid SCHEMBL1039218 | 0.79 | ALDH1A1 (0.54) | AKR1C3KDM1AKMT2ATSHRL3MBTL1 | |
| SCHEMBL7993205 | 0.79 | FNTA (0.55) | KDM1AMAOAMAOB | |
| SCHEMBL7993202 | 0.79 | FNTA (0.55) | KDM1AMAOAMAOB | |
| SCHEMBL11545748 | 0.78 | MAPT (0.55) | HTTKDM1AMAOAMAOBKMT2A | |
| SCHEMBL10586175 | 0.77 | AKR1C3 (0.75) | AKR1C3KMT2AL3MBTL1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0397556-B1 | N-Phenyl amides, methods for their preparation and medicaments containing them | RHONE POULENC SANTE (FR) | 1993-10-20 | — | — | EP | disclosed |
| EP-0397556-A1 | N-Phenyl amides, methods for their preparation and medicaments containing them | RHONE-POULENC SANTE (FR) | 1990-11-14 | — | — | EP | disclosed |