Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.65 |
| ▸ | HRH1 | P35367 | 4/20 | 0.64 |
| ▸ | DRD3 | P35462 | 4/20 | 0.64 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.64 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.64 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.64 |
| ▸ | HRH2 | P25021 | 2/20 | 0.64 |
| ▸ | HTR2A | P28223 | 2/20 | 0.64 |
| ▸ | HTR2B | P41595 | 2/20 | 0.64 |
| ▸ | USP2 | O75604 | 2/20 | 0.64 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.64 |
| ▸ | TEK | Q02763 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | DRD2 | P14416 | 2/20 | 0.60 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.60 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.60 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.60 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.60 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.60 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17549667 | 0.92 | SLC6A4 (0.67) | HTR1ASLC6A4SLC6A3TDP1LMNA | |
| SCHEMBL27520894 | 0.88 | HRH1 (0.72) | HTR1AHRH1DRD3KCNH2SLC6A4 | |
| SCHEMBL14578037 | 0.88 | KMT2A (0.66) | HTR1AHRH1DRD3KCNH2SLC6A4 | |
| Hydrochloric Acid SCHEMBL5372363 | 0.87 | KMT2A (0.64) | HTR1AHRH1DRD3KCNH2SLC6A4 | |
| SCHEMBL17549656 | 0.86 | SLC6A4 (0.70) | HTR1ADRD3SLC6A4SLC6A3HTR2A | |
| SCHEMBL14577890 | 0.84 | DRD3 (0.69) | HTR1AHRH1DRD3KCNH2SLC6A4 | |
| SCHEMBL9178958 | 0.84 | DRD3 (0.72) | HRH1DRD3KCNH2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL7242706 | 0.83 | DRD3 (0.68) | HTR1AHRH1DRD3KCNH2SLC6A4 | |
| Hydrochloric Acid SCHEMBL30473057 | 0.82 | HRH1 (0.73) | HRH1DRD3KCNH2SLC6A4SLC6A3 | |
| SCHEMBL13845055 | 0.81 | DRD3 (0.76) | HTR1AHRH1DRD3KCNH2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001079188-A1 | ANTIHISTAMINIC COMPOUNDS | CIPLA LIMITED (IN) | 2001-10-25 | — | — | WO | claimed |
| WO-2001079188-A1 | ANTIHISTAMINIC COMPOUNDS | CIPLA LIMITED (IN) | 2001-10-25 | — | — | WO | disclosed |