Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 4/20 | 0.72 |
| ▸ | DRD3 | P35462 | 4/20 | 0.72 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.72 |
| ▸ | HRH2 | P25021 | 2/20 | 0.72 |
| ▸ | HTR2A | P28223 | 2/20 | 0.72 |
| ▸ | HTR2B | P41595 | 2/20 | 0.72 |
| ▸ | USP2 | O75604 | 2/20 | 0.72 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.72 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.72 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.72 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.72 |
| ▸ | TEK | Q02763 | 1/20 | 0.72 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.68 |
| ▸ | DRD2 | P14416 | 2/20 | 0.64 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.64 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.64 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.64 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.64 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9178958 | 0.92 | DRD3 (0.72) | HRH1DRD3KCNH2HRH2HTR2A | |
| Hydrochloric Acid SCHEMBL30473057 | 0.91 | HRH1 (0.73) | HRH1DRD3KCNH2HRH2HTR2A | |
| SCHEMBL7993207 | 0.88 | HTR1A (0.65) | HRH1DRD3KCNH2HRH2HTR2A | |
| SCHEMBL4136017 | 0.86 | SLC6A9 (0.91) | HRH1DRD3KCNH2HRH2HTR2A | |
| SCHEMBL28935916 | 0.86 | SLC6A9 (0.91) | HRH1DRD3KCNH2HRH2HTR2A | |
| Hydrochloric Acid SCHEMBL4140455 | 0.85 | SLC6A9 (0.89) | HRH1DRD3KCNH2HRH2HTR2A | |
| SCHEMBL13845055 | 0.85 | DRD3 (0.76) | HRH1DRD3KCNH2HRH2HTR2A | |
| SCHEMBL1447035 | 0.85 | DRD3 (0.66) | HRH1DRD3KCNH2HRH2HTR2A | |
| SCHEMBL1405261 | 0.85 | DRD3 (0.76) | HRH1DRD3KCNH2HRH2HTR2A | |
| SCHEMBL7670965 | 0.84 | DRD3 (0.72) | HRH1DRD3KCNH2HRH2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1246323-C | Nitrogen-based camptothecin derivatives | CALIFORNIA PACIFIC MED CENTER (US) | 2006-03-22 | — | — | CN | disclosed |
| CN-1511159-A | Nitrogen-based camptothecin derivatives | ����������̫ƽ��ҽѧ���� | 2004-07-07 | — | — | CN | disclosed |