Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.61 |
| ▸ | DRD2 | P14416 | 2/20 | 0.61 |
| ▸ | HTR2A | P28223 | 2/20 | 0.61 |
| ▸ | HTR7 | P34969 | 2/20 | 0.61 |
| ▸ | HTR6 | P50406 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7996576 | 0.82 | HTR1A (0.59) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL7993985 | 0.81 | HTR1A (0.64) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL8831844 | 0.81 | HTR1A (0.64) | HTR1ADRD2HTR2AHTR7HTR6 | |
| Hydrochloric Acid SCHEMBL7997035 | 0.80 | HTR1A (0.62) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL7285152 | 0.77 | HTR2A (0.67) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL10843227 | 0.77 | HTR2A (0.67) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL30649298 | 0.77 | HTR1A (0.70) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL9601759 | 0.77 | HTR1A (0.70) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL792775 | 0.77 | HTR1A (0.98) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL25335774 | 0.77 | HTR2A (0.67) | HTR1ADRD2HTR2AHTR7HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6284775-B1 | PSYCHOLOGICAL DISORDERS | AVENTIS PHARMACEUTICALS INC. | 2001-09-04 | — | — | US | disclosed |
| US-5371087-A | Antipsychotic, analgesics, anticonvulsant and anxiolytic agent | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1994-12-06 | — | — | US | disclosed |
| US-5229388-A | 3-[4-(1-substituted-4-piperazinyl)butyl]-4-thiazolidinone and related compounds | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1993-07-20 | — | — | US | disclosed |