⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8729619 | 0.75 | — | — | |
| SCHEMBL16288726 | 0.74 | — | — | |
| SCHEMBL9666020 | 0.74 | — | — | |
| SCHEMBL16288724 | 0.74 | — | — | |
| SCHEMBL491153 | 0.73 | — | — | |
| SCHEMBL491241 | 0.73 | — | — | |
| SCHEMBL1019544 | 0.73 | — | — | |
| SCHEMBL8728822 | 0.72 | — | — | |
| SCHEMBL11203655 | 0.71 | — | — | |
| SCHEMBL8541051 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001064675-A1 | CONDENSED THIAZOLAMINES AND THEIR USE AS NEUROPEPTIDE Y5 ANTAGONISTS | NOVARTIS AG (CH) | 2001-09-07 | — | — | WO | disclosed |
| EP-0609058-B1 | Hexahydronaphthalene ester derivatives, their preparation and their therapeutic uses | SANKYO CO (JP) | 1998-12-09 | — | — | EP | disclosed |
| US-5491167-A | INHIBITORS OF CHOLESTEROL BIOSYNTHESIS | SANKYO COMPANY, LIMITED (JP) | 1996-02-13 | — | — | US | disclosed |
| EP-0609058-A2 | Hexahydronaphthalene ester derivatives, their preparation and their therapeutic uses | SANKYO COMPANY LIMITED (JP) | 1994-08-03 | — | — | EP | disclosed |
| EP-0321273-B1 | Thioformamide derivatives | MAY & BAKER LTD (GB) | 1994-04-20 | — | — | EP | disclosed |
| EP-0321274-B1 | Derivatives of thioformamide | MAY & BAKER LTD (GB) | 1994-03-30 | — | — | EP | disclosed |
| US-5185375-A | For treating disorders of smooth muscle contraction, including respiratory, gastrointestinal, urogential; topical for alopecia | MAY & BAKER LIMITED (GB) | 1993-02-09 | — | — | US | disclosed |
| US-5151436-A | Compounds for inhibiting hair loss in men | RHONE-POULENC SANTE (FR) | 1992-09-29 | — | — | US | disclosed |
| EP-0321274-A1 | Derivatives of thioformamide | RHONE POULENC RORER LIMITED (GB) | 1989-06-21 | — | — | EP | disclosed |
| EP-0321273-A2 | Thioformamide derivatives | RHONE POULENC RORER LIMITED (GB) | 1989-06-21 | — | — | EP | disclosed |