Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 6/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9829469 | 0.73 | CNR1 (0.41) | CYP2C19CYP2C9LMNAMAOATP53 | |
| SCHEMBL7114456 | 0.65 | GRIN1 (0.46) | CYP2C19MAOATP53OPRM1OPRD1 | |
| SCHEMBL7114679 | 0.65 | BCHE (0.41) | TP53NPC1ALDH1A1RAB9A | |
| SCHEMBL9830720 | 0.63 | MEN1 (0.45) | CYP2C19CYP2C9TSHRLMNATP53 | |
| SCHEMBL9830460 | 0.62 | CNR1 (0.44) | CYP2C19TSHRLMNAMAOATP53 | |
| SCHEMBL10669282 | 0.62 | CNR1 (0.44) | CYP2C19LMNAMAOATP53NPC1 | |
| SCHEMBL9831187 | 0.61 | CNR1 (0.43) | CYP2C19LMNAMAOATP53NPC1 | |
| SCHEMBL7115255 | 0.61 | POLB (0.56) | CYP2C19CYP1A2 | |
| SCHEMBL9828953 | 0.60 | CNR1 (0.42) | CYP2C19LMNAMAOATP53NPC1 | |
| SCHEMBL9831468 | 0.60 | CNR1 (0.41) | CYP2C19LMNAMAOATP53NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6281208-B1 | E.G., 3,4-DIHYDRO-2-(5-METHOXY-2-(3-(N-METHYL-N-(2-((3,4-METHYLENEDI OXY) PHENOXY)ETHYL)AMINO)PROPOXY)PHENYL)-4-METHYL-3-OXO-2H-1,4-BENZ | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2001-08-28 | — | — | US | disclosed |