Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UGCG | Q16739 | 7/20 | 0.58 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.58 |
| ▸ | HTR1A | P08908 | 1/20 | 0.58 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | ACACB | O00763 | 6/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1088846 | 0.90 | UGCG (0.71) | UGCGPTGS1HTR1AOPRM1HTT | |
| SCHEMBL13081778 | 0.90 | UGCG (0.71) | UGCGPTGS1HTR1AOPRM1HTT | |
| SCHEMBL14069053 | 0.90 | UGCG (0.71) | UGCGPTGS1HTR1AOPRM1HTT | |
| SCHEMBL1088358 | 0.90 | UGCG (0.71) | UGCGPTGS1HTR1AOPRM1HTT | |
| SCHEMBL25797566 | 0.85 | UGCG (0.53) | UGCGPTGS1HTR1AOPRM1HTT | |
| SCHEMBL20215543 | 0.85 | UGCG (0.53) | UGCGPTGS1HTR1AOPRM1HTT | |
| SCHEMBL7923172 | 0.84 | UGCG (0.58) | UGCGPTGS1HTR1AOPRM1PTGS2 | |
| SCHEMBL14668855 | 0.84 | UGCG (0.51) | UGCGPTGS1HTR1AOPRM1HTT | |
| SCHEMBL20215544 | 0.83 | UGCG (0.52) | UGCGPTGS1HTR1AOPRM1HTT | |
| SCHEMBL20214902 | 0.83 | UGCG (0.84) | UGCGPTGS1HTR1AOPRM1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009117150-A2 | METHOD OF TREATING LUPUS WITH CERAMIDE DERIVATIVES | GENZYME CORPORATION (US) | 2009-09-24 | — | — | WO | disclosed |