Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHPS | P49366 | 19/20 | 0.60 |
| ▸ | EDNRB | P24530 | 1/20 | 0.44 |
| ▸ | EDNRA | P25101 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7993509 | 0.89 | DHPS (0.49) | DHPSEDNRBEDNRA | |
| SCHEMBL4066788 | 0.84 | DHPS (0.85) | DHPSEDNRBEDNRA | |
| SCHEMBL2640206 | 0.80 | DHPS (0.62) | DHPSEDNRBEDNRA | |
| SCHEMBL7979334 | 0.80 | DHPS (0.61) | DHPS | |
| SCHEMBL7996807 | 0.79 | DHPS (0.53) | DHPSEDNRBEDNRA | |
| SCHEMBL7993827 | 0.78 | DHPS (0.52) | DHPSEDNRA | |
| SCHEMBL7990488 | 0.78 | DHPS (0.52) | DHPSEDNRA | |
| SCHEMBL30412442 | 0.76 | DHPS (1.00) | DHPSEDNRBEDNRA | |
| SCHEMBL28573181 | 0.76 | DHPS (1.00) | DHPSEDNRBEDNRA | |
| SCHEMBL7993376 | 0.75 | DHPS (0.55) | DHPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001081338-A1 | SUBSTITUTED SULFONYLAMINOPYRIMIDINES | ACTELION PHARMACEUTICALS LTD (CH) | 2001-11-01 | — | — | WO | disclosed |