Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA1 | P02708 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10734147 | 0.95 | CHRNA1 (0.33) | CHRNA1CHRNA3CHRNA7ALDH1A1NPSR1 | |
| 2-(Nitromethylene)Imidazolidine SCHEMBL2069003 | 0.90 | — | — | |
| 2-(Nitromethylene)Imidazolidine SCHEMBL28204674 | 0.88 | — | — | |
| 2-(Nitromethylene)Imidazolidine SCHEMBL27366555 | 0.88 | — | — | |
| Acetic Acid SCHEMBL27365738 | 0.87 | — | — | |
| SCHEMBL7159324 | 0.73 | — | — | |
| SCHEMBL11554145 | 0.73 | — | — | |
| SCHEMBL7159320 | 0.73 | — | — | |
| SCHEMBL7820589 | 0.71 | FKBP5 (0.38) | CHRNA1CHRNA3CHRNA7ALDH1A1NPSR1 | |
| SCHEMBL7820583 | 0.71 | FKBP5 (0.38) | CHRNA1CHRNA3CHRNA7ALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107880041-A | synthesis of pyrido [1, 2-a ] pyrimidine compound by microwave radiation one-pot method | 南京工业大学 | 2018-04-06 | — | — | CN | claimed |
| WO-2017109795-A1 | NOVEL COMPOUNDS USEFUL AS POTENTIAL INSECT ANTIFEEDANT AND A PROCESS FOR THE PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2017-06-29 | — | — | WO | claimed |
| CN-1052240-A | The composition pesticide of stabilisation | NIHON TOKUSHU NOYAKU SEIZO KK (JP) | 1991-06-19 | — | — | CN | claimed |
| CN-1052241-A | The composition pesticide of stabilisation | NIHON TOKUSHU NOYAKU SEIZO KK (JP) | 1991-06-19 | — | — | CN | claimed |
| EP-0199974-A2 | Nitromethylene-tetrahydropyrimidine | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1986-11-05 | — | — | EP | claimed |
| CN-110357892-B | Tetrahydropyrimidino [1,2-a ] indole derivative and synthesis method and application thereof | 云南大学 | 2022-06-07 | — | — | CN | disclosed |
| CN-109879875-B | Isoquinoline derivatives, synthesis method and anti-tumor application | 云南大学 | 2021-09-03 | — | — | CN | disclosed |
| WO-2020012357-A1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE | INTEGRAL BIOSCIENCES PVT. LTD. (IN) | 2020-01-16 | — | — | WO | disclosed |
| CN-110357892-A | Tetrahydropyrimidine simultaneously [1,2-a] indole derivatives and its synthetic method and application | 云南大学 | 2019-10-22 | — | — | CN | disclosed |
| CN-109879875-A | Isoquinoline class derivate and synthetic method and antitumor application thereof | 云南大学 | 2019-06-14 | — | — | CN | disclosed |
| WO-2017109795-A1 | NOVEL COMPOUNDS USEFUL AS POTENTIAL INSECT ANTIFEEDANT AND A PROCESS FOR THE PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2017-06-29 | — | — | WO | disclosed |
| CN-101812078-A | Heterocyclic dihydropyridine compound and synthesis method thereof | UNIV YUNNAN | 2010-08-25 | — | — | CN | disclosed |
| US-4590272-A | INSECTICIDES, MITICIDES, NEMATOCIDES | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1986-05-20 | — | — | US | disclosed |
| EP-0154178-A1 | Nitromethylene derivatives, method for their preparation and insecticidal, miticidal and nematicidal agents | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1985-09-11 | — | — | EP | disclosed |
| EP-0136636-A2 | Nitromethylene-tetrahydropyrimidine derivatives, process for their preparation and insecticidal, miticidal, tickicidal, and nematicidal means | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1985-04-10 | — | — | EP | disclosed |
| US-4002765-A | 2-(Nitromethylene)-1,3-diazacycloalkane insect control agents | SHELL OIL COMPANY (US) | 1977-01-11 | — | — | US | disclosed |
| US-3971774-A | INSECTICIDE | SHELL OIL COMPANY (US) | 1976-07-27 | — | — | US | disclosed |
| US-3969354-A | INSECTICIDE | SHELL OIL COMPANY (US) | 1976-07-13 | — | — | US | disclosed |
| US-3969354-A | INSECTICIDE | SHELL OIL COMPANY (US) | 1976-07-13 | — | — | US | disclosed |
| US-3948934-A | 2-(Nitromethylene)-1,3-diazacycloalkane insect control agents | SHELL OIL COMPANY (US) | 1976-04-06 | — | — | US | disclosed |