SCHEMBL7994031

SCHEMBL7994031

CCC(C)=C(CC)C(N)=O

nearest known ligand 0.40

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.40
ALDH1A1 P00352 1/20 0.40
ALOX15 P16050 2/20 0.37
LMNA P02545 1/20 0.37
BLM P54132 1/20 0.37
PMP22 Q01453 1/20 0.37
FFAR3 O14843 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7994025 1.00 TDP1 (0.40) TDP1ALDH1A1ALOX15LMNABLM
SCHEMBL5253704 0.82
SCHEMBL9152062 0.82 ALDH1A1 (0.39) TDP1ALDH1A1FFAR3
SCHEMBL8688580 0.82 TDP1 (0.41) TDP1ALDH1A1ALOX15LMNABLM
SCHEMBL1831174 0.82 TDP1 (0.41) TDP1ALDH1A1ALOX15LMNABLM
SCHEMBL1831176 0.82 TDP1 (0.41) TDP1ALDH1A1ALOX15LMNABLM
SCHEMBL1518639 0.80 PAOX (0.38) TDP1ALDH1A1ALOX15LMNABLM
Ammonia Solution, Strong SCHEMBL20210811 0.80 TDP1 (0.42) TDP1ALDH1A1ALOX15LMNABLM
SCHEMBL3355792 0.80
SCHEMBL28289215 0.79 CES1 (0.43) TDP1ALDH1A1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112334553-B Polyurethane composition with long processing time and high strength SIKA技术股份公司 2022-05-17 CN disclosed
CN-109476769-A METHOD FOR SEPARATING CATALYST COMPONENT 日本瑞翁株式会社 2019-03-15 CN disclosed
CN-105722909-B Pneumatic tire 住友橡胶工业株式会社 2018-04-06 CN disclosed
CN-105101935-B Curable composition 可乐丽则武齿科株式会社 2018-02-23 CN disclosed
CN-107300831-A A kind of curable compositions solidified applied to LED light 常州强力电子新材料股份有限公司 2017-10-27 CN disclosed
US-6291530-B1 Aryl-substituted acrylamides with Leukotriene B4 (LTB-4) receptor antagonist activity NOVARTIS AG (CH) 2001-09-18 US disclosed
EP-0942903-A1 ARYL-SUBSTITUTED ACRYLAMIDES WITH LEUKOTRIENE B4 (LTB-4) RECEPTOR ANTAGONIST ACTIVITY Novartis AG (CH) 1999-09-22 EP disclosed
WO-1998013347-A1 ARYL-SUBSTITUTED ACRYLAMIDES WITH LEUKOTRIENE B4 (LTB-4) RECEPTOR ANTAGONIST ACTIVITY NOVARTIS AG (CH) 1998-04-02 WO disclosed