Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 9/20 | 0.57 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.52 |
| ▸ | TNKS | O95271 | 7/20 | 0.48 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
| ▸ | JAK3 | P52333 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31285840 | 1.00 | PGR (0.57) | PGROPRM1TNKSHSD11B1TNKS2 | |
| Hydrochloric Acid SCHEMBL16876811 | 0.99 | PGR (0.56) | PGROPRM1TNKSHSD11B1TNKS2 | |
| SCHEMBL20338373 | 0.93 | PGR (0.60) | PGROPRM1TNKSHSD11B1TNKS2 | |
| SCHEMBL2636697 | 0.92 | PGR (0.52) | PGROPRM1TNKSHSD11B1TNKS2 | |
| SCHEMBL2636696 | 0.92 | PGR (0.52) | PGROPRM1TNKSHSD11B1TNKS2 | |
| SCHEMBL4444315 | 0.89 | TNKS (0.59) | PGROPRM1TNKSHSD11B1TNKS2 | |
| Hydrochloric Acid SCHEMBL16876826 | 0.88 | TNKS (0.58) | PGROPRM1TNKSHSD11B1TNKS2 | |
| SCHEMBL18203563 | 0.82 | PGR (0.50) | PGROPRM1JAK2JAK3 | |
| SCHEMBL8242664 | 0.82 | TNKS (0.64) | PGROPRM1TNKSHSD11B1TNKS2 | |
| SCHEMBL2636830 | 0.82 | TNKS (0.54) | PGROPRM1TNKSHSD11B1TNKS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111848598-A | Heterocyclic ring-containing compound, application thereof and composition containing heterocyclic ring-containing compound | 健艾仕生物医药有限公司 | 2020-10-30 | — | — | CN | disclosed |
| WO-2020216378-A1 | HETEROCYCLIC COMPOUND, APPLICATION THEREOF, AND COMPOSITION CONTAINING SAME | 健艾仕生物医药有限公司 | 2020-10-29 | — | — | WO | disclosed |
| WO-2009124883-A1 | NOVEL 1,3-DIHYDRO-BENZOIMIDAZOL-2-ONES AS M1 AGONISTS | H. LUNDBECK A/S (DK) | 2009-10-15 | — | — | WO | disclosed |
| WO-2009124882-A1 | NOVEL PIPERIDINYL-1,3-DIHYDRO-BENZOIMIDAZOL-2-ONES AS M1 AGONISTS | H. LUNDBECK A/S (DK) | 2009-10-15 | — | — | WO | disclosed |