Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR4 | O95977 | 6/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9748883 | 0.87 | PTGER1 (0.44) | TDP1PPARGMAPTLMNAKDM4E | |
| SCHEMBL7991816 | 0.81 | S1PR4 (0.54) | S1PR4TDP1MAPTLMNAL3MBTL1 | |
| SCHEMBL8561996 | 0.78 | PPARG (0.46) | PPARGKDM4ENPC1ALDH1A1RAB9A | |
| SCHEMBL8567203 | 0.78 | PPARG (0.39) | PPARG | |
| SCHEMBL8566440 | 0.78 | BRS3 (0.37) | S1PR4PPARGMAPTLMNAHPGD | |
| SCHEMBL10649033 | 0.76 | HRH3 (0.47) | HRH3 | |
| SCHEMBL2194287 | 0.75 | PPARG (0.50) | PPARGMAPTLMNAL3MBTL1HTT | |
| SCHEMBL10648674 | 0.74 | HRH3 (0.47) | MAPTLMNAHRH3 | |
| SCHEMBL9746834 | 0.74 | PPARG (0.50) | PPARGMAPTHPGDKDM4EGRM5 | |
| SCHEMBL9747708 | 0.74 | PPARG (0.44) | TDP1PPARGMAPTLMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001096335-A1 | IMIDAZO[1,2-A]PYRIDINE ETHER COMPOUNDS AS ION CHANNEL MODULATORS | CARDIOME PHARMA CORP. (CA) | 2001-12-20 | — | — | WO | disclosed |