Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | BDKRB2 | P30411 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8562316 | 0.90 | HSD11B1 (0.46) | PPARGCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL9748883 | 0.85 | PTGER1 (0.44) | PPARGCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL8563420 | 0.85 | PPARG (0.46) | PPARG | |
| SCHEMBL8566849 | 0.84 | PPARG (0.40) | PPARGBDKRB2 | |
| SCHEMBL8563624 | 0.83 | BDKRB2 (0.41) | BDKRB2 | |
| SCHEMBL2191580 | 0.82 | CYP3A4 (0.48) | PPARGCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL2194287 | 0.82 | PPARG (0.50) | PPARGCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL9076921 | 0.82 | PPARG (0.41) | PPARGCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL8561187 | 0.82 | KMT2A (0.42) | PPARGCYP1A2CYP3A4CYP2D6CYP2C9 | |
| Hydrochloric Acid SCHEMBL8666495 | 0.82 | BDKRB2 (0.42) | BDKRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0596406-B1 | Imidazo (1,2-a) Pyridines as bradykinin antagonists | FUJISAWA PHARMACEUTICAL CO (JP) | 1998-12-16 | — | — | EP | disclosed |
| US-5574042-A | ANTAGONIST FOR BRADYKININS AS ANTIALLERGENS, AUTOIMMUNE DISEASES, ANTIINFLAMMATORY AGENTS, SHOCK OR PAIN | FUJISAWA PHARMACEUTICAL CO., LTD (JP) | 1996-11-12 | — | — | US | disclosed |
| EP-0596406-A1 | Imidazo (1,2-a) Pyridines as bradykinin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-05-11 | — | — | EP | disclosed |