Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.37 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.31 |
| ▸ | FNTA | P49354 | 1/20 | 0.30 |
| ▸ | FNTB | P49356 | 1/20 | 0.30 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4387548 | 0.86 | HRH3 (0.36) | HRH3HAO1FNTAFNTBPGGT1B | |
| SCHEMBL4387545 | 0.72 | HRH3 (0.36) | HRH3HAO1 | |
| SCHEMBL4388946 | 0.66 | — | — | |
| SCHEMBL2105057 | 0.65 | CHRM2 (0.41) | CYP2D6 | |
| SCHEMBL9090439 | 0.64 | CYP19A1 (0.55) | — | |
| SCHEMBL7991000 | 0.64 | HRH3 (0.39) | HRH3HAO1CYP2D6 | |
| SCHEMBL4954449 | 0.63 | HRH3 (0.47) | HRH3HAO1EGLN1CYP2D6HRH4 | |
| SCHEMBL2104158 | 0.63 | CHRM2 (0.41) | HRH3CYP2D6 | |
| SCHEMBL9090407 | 0.62 | CYP19A1 (0.62) | — | |
| SCHEMBL6588101 | 0.62 | RIPK1 (0.38) | CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248765-B1 | ANTIINFLAMMATORY AGENTS; HYPOTENSIVE AGENTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICAL (FR) | 2001-06-19 | — | — | US | claimed |