Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.49 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.49 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4485819 | 0.84 | MAPT (0.56) | MAPTL3MBTL1KCNH2ALDH1A1GAA | |
| SCHEMBL4431238 | 0.79 | CYP11B1 (0.49) | CYP11B1CYP11B2RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL14967225 | 0.76 | NPC1 (0.44) | CYP11B1CYP11B2RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL7998441 | 0.76 | NPC1 (0.54) | CYP19A1RAB9ANPC1SMN1; SMN2L3MBTL1 | |
| SCHEMBL6500018 | 0.76 | POLB (0.58) | MAPTCYP19A1CYP11B1CYP11B2RAB9A | |
| SCHEMBL11292187 | 0.75 | KCNH2 (0.61) | MAPTRAB9ANPC1SMN1; SMN2KCNH2 | |
| SCHEMBL3502988 | 0.75 | LMNA (0.60) | MAPTRAB9ASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL14967550 | 0.75 | POLB (0.55) | ALDH1A1POLB | |
| SCHEMBL11280948 | 0.74 | GAA (0.48) | MAPTCYP19A1CYP11B1CYP11B2RAB9A | |
| SCHEMBL11175467 | 0.74 | MAPT (0.54) | MAPTCYP19A1CYP11B1CYP11B2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024168196-A1 | SYSTEMS AND METHODS FOR ENZYMATIC SYNTHESIS OF POLYNUCLEOTIDES CONTAINING NON-STANDARD NUCLEOTIDE BASEPAIRS | UNIVERSITY OF WASHINGTON (US) | 2024-08-15 | — | — | WO | disclosed |
| WO-2001077077-A1 | SUBSTITUTED (HETERO)ARYL CARBOXAMIDE DERIVATIVES AS MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN (MTP) AND APOLIPOPROTEIN B (APO B) SECRETION | NOVARTIS AG (CH) | 2001-10-18 | — | — | WO | disclosed |