Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.35 |
| ▸ | TSHR | P16473 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | SPHK2 | Q9NRA0 | 4/20 | 0.34 |
| ▸ | SPHK1 | Q9NYA1 | 4/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.34 |
| ▸ | CETP | P11597 | 3/20 | 0.34 |
| ▸ | GMNN | O75496 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4936947 | 0.83 | MEN1 (0.38) | MEN1KMT2ACYP3A4CYP2D6CYP1A2 | |
| SCHEMBL15414718 | 0.78 | — | — | |
| SCHEMBL691872 | 0.75 | MEN1 (0.46) | MEN1KMT2ACYP3A4CYP2D6CYP1A2 | |
| SCHEMBL691873 | 0.75 | MEN1 (0.46) | MEN1KMT2ACYP3A4CYP2D6CYP1A2 | |
| SCHEMBL5132095 | 0.74 | FAAH (0.50) | MEN1KMT2ACYP3A4CYP2D6CYP1A2 | |
| SCHEMBL10897479 | 0.72 | ABCG2 (0.49) | MEN1KMT2ACYP3A4CYP2D6CYP1A2 | |
| SCHEMBL10897482 | 0.72 | ABCG2 (0.49) | MEN1KMT2ACYP3A4CYP2D6CYP1A2 | |
| SCHEMBL2127988 | 0.72 | TSHR (0.41) | MEN1KMT2ACYP3A4CYP2D6CYP1A2 | |
| SCHEMBL27990185 | 0.71 | MEN1 (0.39) | MEN1KMT2ACYP3A4CYP2D6CYP1A2 | |
| SCHEMBL50913 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001000607-A1 | CYCLOHEXENONE DERIVATIVES OF BICYCLIC BENZOIC ACIDS AS HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 2001-01-04 | — | — | WO | disclosed |