Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF2R | P11717 | 5/20 | 0.85 |
| ▸ | FBP1 | P09467 | 1/20 | 0.54 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.47 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.47 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | AMDHD2 | Q9Y303 | 1/20 | 0.44 |
| ▸ | TLR4 | O00206 | 1/20 | 0.44 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.43 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.43 |
| ▸ | LGALS4 | P56470 | 1/20 | 0.43 |
| ▸ | GBA1 | P04062 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1871036 | 1.00 | IGF2R (0.85) | IGF2RFBP1LPAR3LPAR1LPAR2 | |
| SCHEMBL7993492 | 0.95 | IGF2R (0.80) | IGF2RFBP1MAPK1AMDHD2TLR4 | |
| SCHEMBL7980720 | 0.89 | IGF2R (0.74) | IGF2RFBP1AMDHD2 | |
| SCHEMBL28098088 | 0.87 | IGF2R (0.64) | IGF2RFBP1LPAR3LPAR1LPAR2 | |
| SCHEMBL19660846 | 0.85 | IGF2R (0.76) | IGF2RFBP1MAPK1AMDHD2LGALS8 | |
| SCHEMBL19929291 | 0.84 | IGF2R (0.67) | IGF2RFBP1AMDHD2 | |
| SCHEMBL2615799 | 0.84 | IGF2R (0.75) | IGF2RFBP1MAPK1AMDHD2LGALS8 | |
| SCHEMBL933188 | 0.84 | IGF2R (0.75) | IGF2RFBP1MAPK1AMDHD2LGALS8 | |
| SCHEMBL21470012 | 0.83 | IGF2R (0.78) | IGF2RFBP1AMDHD2LGALS8LGALS3 | |
| SCHEMBL19509824 | 0.83 | IGF2R (0.78) | IGF2RFBP1AMDHD2LGALS8LGALS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6294521-B1 | SUGAR PHOSPHATES | AUSTRALIAN NATIONAL UNIVERSITY (AU) | 2001-09-25 | — | — | US | disclosed |