SCHEMBL1871036

SCHEMBL1871036

CCCCCCCCCCCCO[C@@H]1O[C@H](COP(=O)(O)O)[C@@H](O)[C@H](O)[C@H]1O

nearest known ligand 0.85

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ IGF2R P11717 5/20 0.85
▸ FBP1 P09467 1/20 0.54
▸ LPAR3 Q9UBY5 3/20 0.47
▸ LPAR1 Q92633 2/20 0.47
▸ LPAR2 Q9HBW0 2/20 0.47
▸ MAPK1 P28482 1/20 0.47
▸ AMDHD2 Q9Y303 1/20 0.44
▸ TLR4 O00206 1/20 0.44
▸ LGALS8 O00214 1/20 0.43
▸ LGALS3 P17931 1/20 0.43
▸ LGALS4 P56470 1/20 0.43
▸ GBA1 P04062 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7995162 1.00 IGF2R (0.85) IGF2RFBP1LPAR3LPAR1LPAR2
SCHEMBL7993492 0.95 IGF2R (0.80) IGF2RFBP1MAPK1AMDHD2TLR4
SCHEMBL7980720 0.89 IGF2R (0.74) IGF2RFBP1AMDHD2
SCHEMBL28098088 0.87 IGF2R (0.64) IGF2RFBP1LPAR3LPAR1LPAR2
SCHEMBL19660846 0.85 IGF2R (0.76) IGF2RFBP1MAPK1AMDHD2LGALS8
SCHEMBL19929291 0.84 IGF2R (0.67) IGF2RFBP1AMDHD2
SCHEMBL2615799 0.84 IGF2R (0.75) IGF2RFBP1MAPK1AMDHD2LGALS8
SCHEMBL933188 0.84 IGF2R (0.75) IGF2RFBP1MAPK1AMDHD2LGALS8
SCHEMBL21470012 0.83 IGF2R (0.78) IGF2RFBP1AMDHD2LGALS8LGALS3
SCHEMBL19509824 0.83 IGF2R (0.78) IGF2RFBP1AMDHD2LGALS8LGALS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2192924-B1 SACCHARIDE-CONTAINING PROTEIN CONJUGATES AND USES THEREOF PROTALIX LTD (IL) 2017-10-11 — — EP disclosed
US-20140256017-A1 SACCHARIDE-CONTAINING PROTEIN CONJUGATES AND USES THEREOF PROTALIX LTD. (IL) 2014-09-11 — — US disclosed
US-8742079-B2 Saccharide-containing protein conjugates and uses thereof PROTALIX LTD. (IL) 2014-06-03 — — US disclosed
US-20110105379-A1 SACCHARIDE-CONTAINING PROTEIN CONJUGATES AND USES THEREOF PROTALIX LTD. (IL) 2011-05-05 — — US disclosed
EP-2192924-A2 SACCHARIDE-CONTAINING PROTEIN CONJUGATES AND USES THEREOF Protalix Ltd. (IL) 2010-06-09 — — EP disclosed
WO-2009024977-A2 SACCHARIDE-CONTAINING PROTEIN CONJUGATES AND USES THEREOF PROTALIX LTD. (IL) 2009-02-26 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140256017-A1 SACCHARIDE-CONTAINING PROTEIN CONJUGATES AND USES THEREOF STT3B, STT3A, DDOST IGF2R 295/4885FBP1 527/4885LPAR3 4481/4885
US-20110105379-A1 SACCHARIDE-CONTAINING PROTEIN CONJUGATES AND USES THEREOF STT3B, STT3A, DDOST IGF2R 295/4885FBP1 527/4885LPAR3 4481/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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