Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | FPR2 | P25090 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3939459 | 0.78 | CNR2 (0.38) | CA12CA1CA9CA2KDM4E | |
| SCHEMBL16160604 | 0.78 | CNR2 (0.38) | CA12CA1CA9CA2KDM4E | |
| SCHEMBL28310283 | 0.78 | CA12 (0.45) | CA12CA1CA9CA2KDM4E | |
| SCHEMBL16160600 | 0.78 | CNR2 (0.38) | CA12CA1CA9CA2KDM4E | |
| SCHEMBL30467117 | 0.77 | CA12 (0.35) | CA12CA1CA9CA2 | |
| SCHEMBL22917543 | 0.77 | CA12 (0.35) | CA12CA1CA9CA2SMN1; SMN2 | |
| SCHEMBL1150296 | 0.76 | CA12 (0.44) | CA12CA1CA9CA2KDM4E | |
| SCHEMBL29022309 | 0.76 | CA12 (0.44) | CA12CA1CA9CA2KDM4E | |
| SCHEMBL1767824 | 0.75 | CA12 (0.36) | CA12CA1CA9CA2KDM4E | |
| SCHEMBL22917542 | 0.74 | CA12 (0.33) | CA12CA1CA9CA2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009146182-A1 | TRPV4 ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-12-03 | — | — | WO | disclosed |