Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22917542 | 0.86 | CA12 (0.33) | CA12CA1CA2CA9FKBP1A | |
| SCHEMBL22917626 | 0.79 | CA12 (0.35) | CA12CA1CA2CA9FKBP1A | |
| SCHEMBL14558068 | 0.79 | CA12 (0.35) | CA12CA1CA2CA9FKBP1A | |
| SCHEMBL7995182 | 0.77 | CA12 (0.39) | CA12CA1CA2CA9SMN1; SMN2 | |
| SCHEMBL23698589 | 0.76 | ALDH1A1 (0.34) | CA12CA1CA2CA9FKBP1A | |
| SCHEMBL25081496 | 0.72 | PKM (0.31) | CA12CA1CA2CA9SMN1; SMN2 | |
| SCHEMBL30467117 | 0.71 | CA12 (0.35) | CA12CA1CA2CA9 | |
| SCHEMBL21348187 | 0.71 | PIK3CD (0.32) | — | |
| SCHEMBL27393148 | 0.70 | MAPT (0.40) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL19388466 | 0.70 | SMN1; SMN2 (0.46) | CA12CA1CA2CA9FKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021016102-A1 | INHIBITORS OF TYROSINE KINASE | BRIDGENE BIOSCIENCES, INC. (US) | 2021-01-28 | — | — | WO | disclosed |