SCHEMBL7995293

SCHEMBL7995293

CC(C)(C)c1ccc(-c2ccccc2Nc2cc[c]cc2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNK18 Q7Z418 1/20 0.39
CHRM3 P20309 1/20 0.36
ABCG2 Q9UNQ0 1/20 0.36
CCR4 P51679 1/20 0.36
S1PR1 P21453 1/20 0.35
KIF11 P52732 3/20 0.35
FABP3 P05413 1/20 0.34
FABP4 P15090 1/20 0.34
FABP5 Q01469 1/20 0.34
NPC1 O15118 4/20 0.34
RAB9A P51151 4/20 0.34
ALDH1A1 P00352 2/20 0.34
L3MBTL1 Q9Y468 2/20 0.34
GLA P06280 1/20 0.34
ATM Q13315 1/20 0.34
KDR P35968 2/20 0.33
AKR1C3 P42330 1/20 0.33
AKR1C2 P52895 1/20 0.33
MEN1 O00255 1/20 0.33
NR2F2 P24468 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25450282 0.89 KCNK18 (0.44) KCNK18CHRM3ABCG2CCR4S1PR1
SCHEMBL5358209 0.89 KIF11 (0.44) KCNK18CHRM3ABCG2CCR4S1PR1
SCHEMBL29407530 0.85 ABCG2 (0.48) KCNK18ABCG2FABP3FABP4FABP5
SCHEMBL21226201 0.85 ABCG2 (0.48) KCNK18ABCG2FABP3FABP4FABP5
SCHEMBL29099907 0.84 ABCG2 (0.47) KCNK18ABCG2S1PR1KIF11FABP3
SCHEMBL15449530 0.81 KIF11 (0.38) KCNK18CHRM3ABCG2CCR4S1PR1
SCHEMBL27181947 0.80 KCNK18 (0.40) KCNK18ABCG2CCR4KIF11NPC1
SCHEMBL16428719 0.79 ABCG2 (0.40) KCNK18ABCG2CCR4KIF11KDR
SCHEMBL1242289 0.77 TRPV1 (0.50) CHRM3KIF11NPC1RAB9AAKR1C3
SCHEMBL27201590 0.76 KCNK18 (0.40) KCNK18ABCG2FABP3FABP4FABP5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2001006878-A THIN FILM EL ELEMENT AND ITS DRIVING METHOD MATSUSHITA ELECTRIC IND CO LTD 2001-01-12 JP disclosed