Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 20/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4956620 | 0.90 | F10 (0.77) | F10 | |
| SCHEMBL12649398 | 0.90 | F10 (0.77) | F10 | |
| SCHEMBL77619 | 0.83 | F10 (0.73) | F10 | |
| SCHEMBL4960100 | 0.80 | F10 (0.72) | F10 | |
| SCHEMBL9288947 | 0.80 | F10 (0.72) | F10 | |
| SCHEMBL13262575 | 0.80 | F10 (0.60) | F10 | |
| SCHEMBL4957741 | 0.80 | RORC (0.49) | F10 | |
| SCHEMBL4283606 | 0.79 | F10 (0.71) | F10CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL20802077 | 0.79 | F10 (0.54) | F10CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL13262557 | 0.79 | F10 (0.75) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010002115-A2 | FXA INHIBITORS WITH CYCLIC AMIDOXIME OR CYCLIC AMIDRAZONE AS P4 SUBUNIT, PROCESSES FOR THEIR PREPARATIONS, AND PHARMACEUTICAL COMPOSITIONS AND DERIVATIVES THEREOF | LEGOCHEM BIOSCIENCE LTD. (KR) | 2010-01-07 | — | — | WO | disclosed |