Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.41 |
| ▸ | NPC1 | O15118 | 5/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | PKM | P14618 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | STAT1 | P42224 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | HTT | P42858 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 2/20 | 0.34 |
| ▸ | MKNK1 | Q9BUB5 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7994114 | 0.83 | MKNK1 (0.40) | SMN1; SMN2MAPTLMNAMKNK1HPGD | |
| SCHEMBL7998616 | 0.79 | SMN1; SMN2 (0.39) | SMN1; SMN2NPC1RAB9APKMALDH1A1 | |
| SCHEMBL7995805 | 0.74 | SMN1; SMN2 (0.56) | SMN1; SMN2NPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL11734584 | 0.69 | CYP1A2 (0.43) | SMN1; SMN2NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL22834815 | 0.69 | CYP1A2 (0.47) | KDM4EMEN1KMT2AHPGDHSD17B10 | |
| SCHEMBL7983668 | 0.68 | CYP1A2 (0.39) | MKNK1 | |
| SCHEMBL8089233 | 0.65 | CYP1A2 (0.36) | ALDH1A1LMNAMKNK1 | |
| SCHEMBL8670922 | 0.64 | SMN1; SMN2 (0.64) | SMN1; SMN2NPC1RAB9APKMMAPT | |
| SCHEMBL1202690 | 0.63 | HTT (0.41) | SMN1; SMN2NPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL7984159 | 0.62 | EGFR (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001034578-A1 | COMPOUNDS WITH ANTI-HELICOBACTER PYLORI ACTIVITY | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | disclosed |