Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 20/20 | 0.79 |
| ▸ | PTPRF | P10586 | 1/20 | 0.47 |
| ▸ | PTPRA | P18433 | 1/20 | 0.47 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.47 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7596766 | 0.89 | PTPN1 (1.00) | PTPN1PTPRFPTPRAPTPN7DUSP3 | |
| SCHEMBL7592978 | 0.81 | PTPN1 (1.00) | PTPN1PTPRFPTPRAPTPN7DUSP3 | |
| SCHEMBL7592982 | 0.81 | PTPN1 (0.79) | PTPN1 | |
| SCHEMBL7595355 | 0.79 | PTPN1 (1.00) | PTPN1 | |
| SCHEMBL7595341 | 0.78 | PTPN1 (1.00) | PTPN1 | |
| SCHEMBL7594997 | 0.74 | PTPN1 (1.00) | PTPN1PTPRFPTPRAPTPN7DUSP3 | |
| SCHEMBL7595011 | 0.74 | PTPN1 (1.00) | PTPN1PTPRFPTPRAPTPN7DUSP3 | |
| SCHEMBL4478559 | 0.69 | PTPN1 (0.79) | PTPN1PTPRFPTPRAPTPN7DUSP3 | |
| SCHEMBL7509762 | 0.69 | PTPN1 (0.65) | PTPN1PTPRFPTPRAPTPN7DUSP3 | |
| SCHEMBL3868415 | 0.69 | PTPN1 (0.97) | PTPN1PTPRFPTPRAPTPN7DUSP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310081-B1 | PROTEIN TYROSINE PHOSPHATASE INHIBITORS | AMERICAN HOME PRODUCTS CORPORATION | 2001-10-30 | — | — | US | disclosed |