Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7592982 | 0.88 | PTPN1 (0.79) | PTPN1 | |
| SCHEMBL7592978 | 0.86 | PTPN1 (1.00) | PTPN1 | |
| SCHEMBL7593258 | 0.85 | PTPN1 (1.00) | PTPN1 | |
| SCHEMBL7595341 | 0.82 | PTPN1 (1.00) | PTPN1 | |
| SCHEMBL7505309 | 0.79 | PTPN1 (0.66) | PTPN1 | |
| SCHEMBL7596766 | 0.79 | PTPN1 (1.00) | PTPN1 | |
| SCHEMBL7995791 | 0.79 | PTPN1 (0.79) | PTPN1 | |
| SCHEMBL7506540 | 0.78 | PTPN1 (1.00) | PTPN1 | |
| SCHEMBL7594997 | 0.72 | PTPN1 (1.00) | PTPN1 | |
| SCHEMBL7595011 | 0.72 | PTPN1 (1.00) | PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1077966-B1 | BIPHENYL SULFONYL ARYL CARBOXYLIC ACIDS USEFUL IN THE TREATMENT OF INSULIN RESISTANCE AND HYPERGLYCEMIA | WYETH CORP (US) | 2002-11-20 | — | — | EP | disclosed |
| US-6310081-B1 | PROTEIN TYROSINE PHOSPHATASE INHIBITORS | AMERICAN HOME PRODUCTS CORPORATION | 2001-10-30 | — | — | US | disclosed |
| US-6221902-B1 | HYPOGLYCEMIC AGENTS; ANTIDIABETIC AGENTS | AMERICAN HOME PRODUCTS CORPORATION | 2001-04-24 | — | — | US | disclosed |