SCHEMBL7995799

SCHEMBL7995799

C=CC[C@H](CC(=O)OC(C)(C)C)C(=O)N1C(=O)OC[C@@H]1I

nearest known ligand 0.37

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
USP2 O75604 3/20 0.37
L3MBTL1 Q9Y468 1/20 0.33
MAN2B1 O00754 1/20 0.31
IL6ST P40189 2/20 0.30
STAT3 P40763 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7428550 0.86 IL6ST (0.45) USP2L3MBTL1IL6STSTAT3
SCHEMBL27586681 0.86 IL6ST (0.45) USP2L3MBTL1IL6STSTAT3
SCHEMBL2192762 0.80 USP2 (0.46) USP2L3MBTL1IL6ST
SCHEMBL2192757 0.80 USP2 (0.46) USP2L3MBTL1IL6ST
SCHEMBL2192756 0.80 USP2 (0.46) USP2L3MBTL1IL6ST
SCHEMBL12418054 0.80 USP2 (0.46) USP2L3MBTL1IL6ST
SCHEMBL7049082 0.80 USP2 (0.46) USP2L3MBTL1IL6ST
SCHEMBL15619032 0.80 USP2 (0.46) USP2L3MBTL1IL6ST
SCHEMBL22036316 0.80 USP2 (0.46) USP2L3MBTL1IL6ST
SCHEMBL7585942 0.78 IL6ST (0.38) USP2L3MBTL1IL6STSTAT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009113320-A1 MMP INHIBITOR 株式会社ヤクルト本社 (JP) 2009-09-17 WO disclosed