Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL6ST | P40189 | 5/20 | 0.45 |
| ▸ | STAT3 | P40763 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 3/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.32 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27586681 | 1.00 | IL6ST (0.45) | IL6STSTAT3USP2PIK3CDL3MBTL1 | |
| SCHEMBL7585942 | 0.91 | IL6ST (0.38) | IL6STSTAT3USP2L3MBTL1 | |
| SCHEMBL7995799 | 0.86 | USP2 (0.37) | IL6STSTAT3USP2L3MBTL1 | |
| SCHEMBL6450744 | 0.86 | IL6ST (0.45) | IL6STSTAT3PIK3CDPLA2G10PLA2G5 | |
| SCHEMBL8211410 | 0.86 | IL6ST (0.45) | IL6STSTAT3PIK3CDPLA2G10PLA2G5 | |
| SCHEMBL8211407 | 0.86 | IL6ST (0.45) | IL6STSTAT3PIK3CDPLA2G10PLA2G5 | |
| SCHEMBL8211409 | 0.86 | IL6ST (0.45) | IL6STSTAT3PIK3CDPLA2G10PLA2G5 | |
| SCHEMBL6432729 | 0.84 | IL6ST (0.50) | IL6STSTAT3PIK3CD | |
| SCHEMBL7280265 | 0.84 | IL6ST (0.43) | IL6STSTAT3PIK3CDPLA2G10PLA2G5 | |
| SCHEMBL7280258 | 0.84 | IL6ST (0.43) | IL6STSTAT3PIK3CDPLA2G10PLA2G5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1133484-A2 | HETEROCYCLIC DERIVATIVES AND THEIR USE AS INTEGRIN INHIBITORS | AstraZeneca AB (SE) | 2001-09-19 | — | — | EP | disclosed |
| WO-2000005223-A2 | HETEROCYCLIC DERIVATIVES AND THEIR USE AS INTEGRIN INHIBITORS | ASTRAZENECA AB (SE) | 2000-02-03 | — | — | WO | disclosed |