Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 12/20 | 0.58 |
| ▸ | MC4R | P32245 | 1/20 | 0.44 |
| ▸ | MC5R | P33032 | 1/20 | 0.44 |
| ▸ | PLAU | P00749 | 2/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.43 |
| ▸ | PLG | P00747 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 4/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.41 |
| ▸ | HPN | P05981 | 1/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.40 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.40 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8003193 | 1.00 | F10 (0.58) | F10MC4RMC5RPLAUITGB3 | |
| SCHEMBL7999904 | 0.95 | F10 (0.53) | F10MC4RMC5RPLAUITGB3 | |
| SCHEMBL7999994 | 0.93 | MC4R (0.54) | F10MC4RMC5RPLAUPLG | |
| SCHEMBL7999912 | 0.93 | MC4R (0.54) | F10MC4RMC5RPLAUPLG | |
| SCHEMBL7986928 | 0.92 | F10 (0.51) | F10PLAUPLGF2PRSS1 | |
| SCHEMBL7999748 | 0.92 | F10 (0.51) | F10PLAUPLGF2PRSS1 | |
| SCHEMBL7986772 | 0.92 | F10 (0.57) | F10MC4RMC5RITGB3ITGA2B | |
| SCHEMBL8000067 | 0.92 | F10 (0.51) | F10MC4RMC5RPLAUF2 | |
| SCHEMBL7996131 | 0.92 | F10 (0.51) | F10MC4RMC5RPLAUF2 | |
| SCHEMBL7986780 | 0.89 | F10 (0.62) | F10ITGB3ITGA2BF2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000008005-A2 | PIPERAZINONE DERIVATIVES | MERCK PATENT GMBH (DE) | 2000-02-17 | — | — | WO | disclosed |