Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 11/20 | 0.53 |
| ▸ | PLAU | P00749 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | MC4R | P32245 | 1/20 | 0.47 |
| ▸ | MC5R | P33032 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | HPN | P05981 | 2/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.45 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.45 |
| ▸ | F2 | P00734 | 3/20 | 0.45 |
| ▸ | CLPP | Q16740 | 1/20 | 0.45 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.44 |
| ▸ | PLG | P00747 | 1/20 | 0.44 |
| ▸ | PROC | P04070 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8000067 | 0.95 | F10 (0.51) | F10PLAUKMT2AMC4RMC5R | |
| SCHEMBL7996131 | 0.95 | F10 (0.51) | F10PLAUKMT2AMC4RMC5R | |
| SCHEMBL7999994 | 0.95 | MC4R (0.54) | F10PLAUKMT2AMC4RMC5R | |
| SCHEMBL7999912 | 0.95 | MC4R (0.54) | F10PLAUKMT2AMC4RMC5R | |
| SCHEMBL8003193 | 0.95 | F10 (0.58) | F10PLAUMC4RMC5RHPN | |
| SCHEMBL7996092 | 0.95 | F10 (0.58) | F10PLAUMC4RMC5RHPN | |
| SCHEMBL7986928 | 0.94 | F10 (0.51) | F10PLAUHPNPRSS1PRSS2 | |
| SCHEMBL7999748 | 0.94 | F10 (0.51) | F10PLAUHPNPRSS1PRSS2 | |
| SCHEMBL7986772 | 0.91 | F10 (0.57) | F10KMT2AMC4RMC5RAPP | |
| SCHEMBL7999835 | 0.89 | F10 (0.58) | F10KMT2AAPPHRH3HPN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000008005-A2 | PIPERAZINONE DERIVATIVES | MERCK PATENT GMBH (DE) | 2000-02-17 | — | — | WO | disclosed |