Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1L1 | Q9UHC9 | 5/20 | 0.72 |
| ▸ | USP2 | O75604 | 4/20 | 0.72 |
| ▸ | LMNA | P02545 | 3/20 | 0.72 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.49 |
| ▸ | OSBP | P22059 | 1/20 | 0.49 |
| ▸ | RORC | P51449 | 1/20 | 0.49 |
| ▸ | OSBP2 | Q969R2 | 1/20 | 0.49 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.49 |
| ▸ | FNTA | P49354 | 3/20 | 0.49 |
| ▸ | FNTB | P49356 | 3/20 | 0.49 |
| ▸ | CDC25A | P30304 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | RORA | P35398 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | SRD5A1 | P18405 | 4/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 4/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7996293 | 0.90 | NPC1L1 (0.61) | NPC1L1USP2LMNAFNTAFNTB | |
| 5Alpha-Cholestan-3Beta-Ol-6-One SCHEMBL7996326 | 0.84 | NPC1L1 (0.96) | NPC1L1USP2LMNAABCB1OSBP | |
| 5Alpha-Cholestan-3Beta-Ol-6-One SCHEMBL14420788 | 0.84 | NPC1L1 (1.00) | NPC1L1USP2LMNAABCB1OSBP | |
| 5Alpha-Cholestan-3Beta-Ol-6-One SCHEMBL14898038 | 0.84 | NPC1L1 (1.00) | NPC1L1USP2LMNAABCB1OSBP | |
| 5Alpha-Cholestan-3Beta-Ol-6-One SCHEMBL4276094 | 0.84 | NPC1L1 (1.00) | NPC1L1USP2LMNAABCB1OSBP | |
| 5Alpha-Cholestan-3Beta-Ol-6-One SCHEMBL248174 | 0.84 | NPC1L1 (1.00) | NPC1L1USP2LMNAABCB1OSBP | |
| 5Alpha-Cholestan-3Beta-Ol-6-One SCHEMBL13429389 | 0.84 | NPC1L1 (1.00) | NPC1L1USP2LMNAABCB1OSBP | |
| 5Alpha-Cholestan-3Beta-Ol-6-One SCHEMBL5341515 | 0.84 | NPC1L1 (1.00) | NPC1L1USP2LMNAABCB1OSBP | |
| 5Alpha-Cholestan-3Beta-Ol-6-One SCHEMBL12430811 | 0.84 | NPC1L1 (1.00) | NPC1L1USP2LMNAABCB1OSBP | |
| 5Alpha-Cholestan-3Beta-Ol-6-One SCHEMBL18407109 | 0.84 | NPC1L1 (1.00) | NPC1L1USP2LMNAABCB1OSBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288041-B1 | Sialic acid derivatives | MITSUBISHI CHEMICAL CORPORATION (JP) | 2001-09-11 | — | — | US | disclosed |
| EP-0837070-A1 | SIALIC ACID DERIVATIVES | MITSUBISHI CHEMICAL CORPORATION (JP) | 1998-04-22 | — | — | EP | disclosed |