Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY6 | Q15077 | 11/20 | 0.66 |
| ▸ | P2RY14 | Q15391 | 4/20 | 0.66 |
| ▸ | NT5E | P21589 | 1/20 | 0.66 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.63 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.63 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.54 |
| ▸ | P2RY2 | P41231 | 2/20 | 0.54 |
| ▸ | ADK | P55263 | 1/20 | 0.51 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7600836 | 1.00 | P2RY6 (0.66) | P2RY6P2RY14NT5EPLA2G1BATG4B | |
| SCHEMBL10796298 | 0.90 | P2RY6 (0.56) | P2RY6P2RY14NT5EPLA2G1BATG4B | |
| SCHEMBL7715730 | 0.87 | P2RY6 (0.53) | P2RY6P2RY14NT5EPLA2G1BATG4B | |
| SCHEMBL11007076 | 0.87 | P2RY6 (0.59) | P2RY6P2RY14NT5EPLA2G1BATG4B | |
| SCHEMBL5390461 | 0.86 | P2RY6 (0.53) | P2RY6P2RY14NT5EPLA2G1BATG4B | |
| SCHEMBL8630139 | 0.86 | PLA2G1B (0.52) | P2RY6P2RY14NT5EPLA2G1BATG4B | |
| SCHEMBL8675898 | 0.86 | P2RY6 (0.60) | P2RY6P2RY14NT5EPLA2G1BATG4B | |
| SCHEMBL8675896 | 0.86 | P2RY6 (0.60) | P2RY6P2RY14NT5EPLA2G1BATG4B | |
| Fosfluridine Tidoxil SCHEMBL7524603 | 0.85 | P2RY6 (0.53) | P2RY6P2RY14NT5EPLA2G1BATG4B | |
| SCHEMBL10795816 | 0.85 | P2RY6 (0.51) | P2RY6P2RY14NT5EPLA2G1BATG4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6025343-A | Lipid esters of nucleoside monophosphates and their use as immunosuppressive drugs | ROCHE DIAGNOSTICS GMBH (DE) | 2000-02-15 | — | — | US | disclosed |