SCHEMBL7996466

SCHEMBL7996466

O=C(/C=C/c1ccc2c(c1)OCO2)c1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 11/20 0.84
RAB9A P51151 7/20 0.84
NPC1 O15118 6/20 0.84
CYP2D6 P10635 5/20 0.75
CYP3A4 P08684 4/20 0.75
CYP1A1 P04798 3/20 0.75
CYP1A2 P05177 3/20 0.75
KDM4E B2RXH2 3/20 0.75
CYP1B1 Q16678 2/20 0.75
CYP2C19 P33261 2/20 0.75
ALDH1A1 P00352 2/20 0.75
CYP2C9 P11712 1/20 0.75
MEN1 O00255 3/20 0.70
LMNA P02545 3/20 0.70
KMT2A Q03164 3/20 0.70
PKM P14618 2/20 0.70
MAPK1 P28482 2/20 0.70
PLIN1 O60240 1/20 0.70
PLIN5 Q00G26 1/20 0.70
ABHD5 Q8WTS1 1/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30382530 1.00 MAPT (0.84) MAPTRAB9ANPC1CYP2D6CYP3A4
SCHEMBL5147081 1.00 MAPT (0.84) MAPTRAB9ANPC1CYP2D6CYP3A4
Chalcone SCHEMBL25195107 0.97 MAPT (0.80) MAPTRAB9ANPC1CYP2D6CYP3A4
SCHEMBL25608287 0.92 MAPT (0.72) MAPTRAB9ANPC1CYP2D6CYP3A4
SCHEMBL25267270 0.92 MAPT (0.72) MAPTRAB9ANPC1CYP2D6CYP3A4
SCHEMBL108665 0.88 MAPT (0.79) MAPTRAB9ANPC1CYP2D6CYP3A4
SCHEMBL28553855 0.88 MAPT (0.79) MAPTRAB9ANPC1CYP2D6CYP3A4
SCHEMBL3440510 0.87 MAPT (0.84) MAPTRAB9ANPC1CYP2D6CYP3A4
SCHEMBL25209543 0.87 MAPT (0.84) MAPTRAB9ANPC1CYP2D6CYP3A4
SCHEMBL3440511 0.87 MAPT (0.84) MAPTRAB9ANPC1CYP2D6CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 US disclosed
US-20250090565-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YewSavin, Inc. (US) 2025-03-20 US disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 WO disclosed
US-20210207175-A1 COMPOUND FOR REGULATING GENE EDITING EFFICIENCY AND APPLICATION THEREOF SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) 2021-07-08 US disclosed
EP-3825409-A1 COMPOUND FOR REGULATING GENE EDITING EFFICIENCY AND APPLICATION THEREOF Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences (CN) 2021-05-26 EP disclosed
WO-2019238091-A1 COMPOUND FOR REGULATING GENE EDITING EFFICIENCY AND APPLICATION THEREOF 中国科学院上海有机化学研究所 2019-12-19 WO disclosed
US-9085520-B2 Composition for treating diabetes and metabolic diseases and a preparation method thereof KAOHSIUNG MEDICAL UNIVERSITY (TW) 2015-07-21 US disclosed
US-9085520-B2 Composition for treating diabetes and metabolic diseases and a preparation method thereof KAOHSIUNG MEDICAL UNIVERSITY (TW) 2015-07-21 US disclosed
US-7598294-B2 Antiproliferative agents; antiinflammatory agents; anticancer agents; diagnosis, therapy SPEAR THERAPEUTICS LIMITED (GB) 2009-10-06 US disclosed
EP-0975224-A1 PROCESS AND COMPOSITIONS FOR ENHANCING RELIABILITY OF EXOGENOUS CHEMICAL SUBSTANCES APPLIED TO PLANTS MONSANTO COMPANY (US) 2000-02-02 EP disclosed
US-6020287-A USING MIXTURE OF HERBICIDE AND PHENYL-SUBSTITUTED OLEFIN COMPOUND MONSANTO COMPANY (US) 2000-02-01 US disclosed
WO-1998033385-A1 PROCESS AND COMPOSITIONS FOR ENHANCING RELIABILITY OF EXOGENOUS CHEMICAL SUBSTANCES APPLIED TO PLANTS MONSANTO COMPANY (US) 1998-08-06 WO disclosed
US-5492915-A ANTIINFLAMMATORY AGENTS RHONE-POULENC RORER S.A. (FR) 1996-02-20 US disclosed
US-5366982-A Antiinflammatory agents or antihistamines RHONE-POULENC RORER S.A. (FR) 1994-11-22 US disclosed
EP-0540604-A1 SUBSTITUTED BICYCLIC BIS-ARYL COMPOUNDS EXHIBITING SELECTIVE LEUKOTRIENE B 4? ANTAGONIST ACTIVITY, THEIR PREPARATION AND USE IN PHARMACEUTICAL COMPOSITIONS Aventis Pharma S.A. (FR) 1993-05-12 EP disclosed
WO-1992001675-A2 SUBSTITUTED BICYCLIC BIS-ARYL COMPOUNDS EXHIBITING SELECTIVE LEUKOTRIENE B4 ANTAGONIST ACTIVITY, THEIR PREPARATION AND USE IN PHARMACEUTICAL COMPOSITIONS RHONE-POULENC RORER S.A. (FR) 1992-02-06 WO disclosed
US-5070001-A LIGHT-SENSITIVE MIXTURE FOR PRODUCING POSITIVE OR NEGATIVE RELIEF COPIES HOECHST AKTIENGESELLSCHAFT (DE) 1991-12-03 US disclosed
US-4264483-A AN ACRYLIC MONOMER OR OLIGOMER, PHOTOREACTIVE RESIN, PHOTOINITIATOR, FREE RADICAL INHIBITOR, PIGMENT WHITTAKER CORPORATION (US) 1981-04-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B MAPT 3297/4885RAB9A 480/4885NPC1 1378/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 MAPT 3512/4885RAB9A 1327/4885NPC1 1908/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 MAPT 3512/4885RAB9A 1327/4885NPC1 1908/4885
US-20210207175-A1 COMPOUND FOR REGULATING GENE EDITING EFFICIENCY AND APPLICATION THEREOF TET2, ZFX, ZFR MAPT 4470/4885RAB9A 3127/4885NPC1 156/4885
US-20250090565-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, TFPI, SERPINE1 MAPT 3522/4885RAB9A 1332/4885NPC1 1961/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.