Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 19/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 2/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7988853 | 0.85 | F10 (0.49) | F10F2ABCB11ST14 | |
| SCHEMBL7994757 | 0.85 | F10 (0.45) | F10F2ABCB11ST14 | |
| SCHEMBL11969084 | 0.83 | MAOA (0.60) | F10MAOAABCB11 | |
| SCHEMBL4761188 | 0.82 | F10 (0.67) | F10F2ABCB11ST14 | |
| SCHEMBL7997701 | 0.81 | F10 (0.45) | F10MAOAF2ABCB11ST14 | |
| SCHEMBL7994144 | 0.79 | F10 (0.43) | F10F2ABCB11ST14 | |
| SCHEMBL11969003 | 0.79 | MAOA (0.47) | F10MAOA | |
| SCHEMBL13428719 | 0.79 | MAOA (0.47) | F10MAOA | |
| SCHEMBL7999551 | 0.79 | GRM2 (0.48) | F10F2ABCB11ST14 | |
| SCHEMBL7982750 | 0.78 | F10 (0.66) | F10F2ABCB11ST14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010002115-A2 | FXA INHIBITORS WITH CYCLIC AMIDOXIME OR CYCLIC AMIDRAZONE AS P4 SUBUNIT, PROCESSES FOR THEIR PREPARATIONS, AND PHARMACEUTICAL COMPOSITIONS AND DERIVATIVES THEREOF | LEGOCHEM BIOSCIENCE LTD. (KR) | 2010-01-07 | — | — | WO | disclosed |