SCHEMBL7996591

SCHEMBL7996591

CCOC(=O)C=Cc1cc(C)c(O)c(C)c1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.68
CA12 O43570 1/20 0.63
CA1 P00915 1/20 0.63
CA2 P00918 1/20 0.63
CA7 P43166 1/20 0.63
CA9 Q16790 1/20 0.63
CA14 Q9ULX7 1/20 0.63
CYP1A2 P05177 1/20 0.62
CYP2D6 P10635 1/20 0.62
CYP2C9 P11712 1/20 0.62
CYP2B6 P20813 1/20 0.62
TTR P02766 1/20 0.62
DPP4 P27487 1/20 0.62
MAOB P27338 1/20 0.56
ALOX5 P09917 1/20 0.54
FDPS P14324 1/20 0.50
PTGS2 P35354 1/20 0.50
MET P08581 1/20 0.50
ESR1 P03372 1/20 0.49
CNKSR1 Q969H4 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2389160 1.00 CYP3A4 (0.68) CYP3A4CA12CA1CA2CA7
SCHEMBL11306366 0.87 CYP3A4 (0.57) CYP3A4CA12CA1CA2CA7
SCHEMBL15473940 0.85 CYP3A4 (0.57) CYP3A4CA12CA1CA2CA7
SCHEMBL10146765 0.85 CYP3A4 (0.57) CYP3A4CA12CA1CA2CA7
SCHEMBL17321170 0.84 APP (0.66) CYP3A4CYP1A2CYP2D6CYP2C9CYP2B6
SCHEMBL27627337 0.84 APP (0.66) CYP3A4CYP1A2CYP2D6CYP2C9CYP2B6
SCHEMBL2303800 0.83 CYP3A4 (0.68) CYP3A4CA12CA1CA2CA7
SCHEMBL2303796 0.83 CYP3A4 (0.68) CYP3A4CA12CA1CA2CA7
SCHEMBL2390177 0.83 CYP3A4 (0.64) CYP3A4CA12CA1CA2CA7
SCHEMBL28354415 0.83 CYP3A4 (0.68) CYP3A4CA12CA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0975224-A1 PROCESS AND COMPOSITIONS FOR ENHANCING RELIABILITY OF EXOGENOUS CHEMICAL SUBSTANCES APPLIED TO PLANTS MONSANTO COMPANY (US) 2000-02-02 EP disclosed
US-6020287-A USING MIXTURE OF HERBICIDE AND PHENYL-SUBSTITUTED OLEFIN COMPOUND MONSANTO COMPANY (US) 2000-02-01 US disclosed
WO-1998033385-A1 PROCESS AND COMPOSITIONS FOR ENHANCING RELIABILITY OF EXOGENOUS CHEMICAL SUBSTANCES APPLIED TO PLANTS MONSANTO COMPANY (US) 1998-08-06 WO disclosed
US-4281080-A TACKIFIERS FOR RUBBERS THE GOODYEAR TIRE & RUBBER COMPANY (US) 1981-07-28 US disclosed
US-4010140-A Age resistant resin compositions and admixtures useful as adhesives THE GOODYEAR TIRE & RUBBER COMPANY (US) 1977-03-01 US disclosed