Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.57 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA7 | P43166 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.52 |
| ▸ | TTR | P02766 | 1/20 | 0.52 |
| ▸ | DPP4 | P27487 | 1/20 | 0.52 |
| ▸ | GABBR2 | O75899 | 2/20 | 0.51 |
| ▸ | GABBR1 | Q9UBS5 | 2/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6910749 | 0.93 | CYP3A4 (0.61) | CYP3A4CA12CA1CA2CA7 | |
| SCHEMBL6910750 | 0.93 | CYP3A4 (0.61) | CYP3A4CA12CA1CA2CA7 | |
| SCHEMBL27904472 | 0.92 | CYP3A4 (0.59) | CYP3A4CA12CA1CA2CA7 | |
| SCHEMBL30648252 | 0.88 | GABBR2 (0.48) | CYP3A4GABBR2GABBR1CYP1A2CYP2D6 | |
| SCHEMBL2803205 | 0.88 | APP (0.49) | CYP3A4GABBR2GABBR1CYP1A2CYP2D6 | |
| SCHEMBL1398396 | 0.88 | GABBR2 (0.48) | CYP3A4GABBR2GABBR1CYP1A2CYP2D6 | |
| SCHEMBL1398397 | 0.88 | GABBR2 (0.48) | CYP3A4GABBR2GABBR1CYP1A2CYP2D6 | |
| SCHEMBL2389160 | 0.87 | CYP3A4 (0.68) | CYP3A4CA12CA1CA2CA7 | |
| SCHEMBL7996591 | 0.87 | CYP3A4 (0.68) | CYP3A4CA12CA1CA2CA7 | |
| SCHEMBL11861585 | 0.86 | CYP3A4 (0.54) | CYP3A4CA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4281080-A | TACKIFIERS FOR RUBBERS | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1981-07-28 | — | — | US | disclosed |
| US-4010140-A | Age resistant resin compositions and admixtures useful as adhesives | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1977-03-01 | — | — | US | disclosed |