Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6920484 | 0.86 | PLAU (0.69) | PLAUC1S | |
| Hydrochloric Acid SCHEMBL6920775 | 0.85 | PLAU (0.68) | PLAUC1S | |
| SCHEMBL6921142 | 0.85 | PLAU (0.63) | PLAUC1S | |
| SCHEMBL13946253 | 0.85 | PLAU (0.61) | PLAUC1S | |
| SCHEMBL6927242 | 0.84 | PLAU (0.66) | PLAUC1S | |
| Hydrochloric Acid SCHEMBL6924811 | 0.84 | PLAU (0.61) | PLAUC1S | |
| SCHEMBL7380452 | 0.82 | PLAU (0.64) | PLAUC1S | |
| SCHEMBL7996788 | 0.81 | PLAU (0.50) | PLAUC1S | |
| SCHEMBL6924620 | 0.81 | PLAU (0.63) | PLAUC1S | |
| SCHEMBL6928673 | 0.81 | PLAU (0.64) | PLAUC1S |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6291514-B1 | Heteroaryl amidines, methylamidines and guanidines, preparation thereof, and use thereof as protease inhibitors | 3-DIMENSIONAL PHARMACEUTICALS, INC. | 2001-09-18 | — | — | US | disclosed |