SCHEMBL547267

SCHEMBL547267

NCC(=O)NCC(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.42
GSTK1 Q9Y2Q3 1/20 0.42
GLO1 Q04760 1/20 0.37
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
ALDH1A1 P00352 1/20 0.35
LMNA P02545 1/20 0.35
MAPT P10636 1/20 0.35
PTGS2 P35354 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
ITGB3 P05106 4/20 0.35
ITGB1 P05556 3/20 0.35
ITGAV P06756 3/20 0.35
ITGA5 P08648 3/20 0.35
MDM4 O15151 1/20 0.35
ECE1 P42892 4/20 0.35
TERT O14746 1/20 0.35
MDM2 Q00987 2/20 0.34
GRIA1 P42261 1/20 0.34
GRIA3 P42263 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3706491 1.00 PTGS1 (0.42) PTGS1GSTK1GLO1MEN1KMT2A
SCHEMBL6675010 0.98 PTGS1 (0.41) PTGS1GSTK1GLO1MEN1KMT2A
SCHEMBL6823837 0.98 PTGS1 (0.41) PTGS1GSTK1GLO1MEN1KMT2A
SCHEMBL7257306 0.98 PTGS1 (0.41) PTGS1GSTK1GLO1MEN1KMT2A
SCHEMBL7571368 0.98 PTGS1 (0.41) PTGS1GSTK1GLO1MEN1KMT2A
SCHEMBL18396457 0.98 PTGS1 (0.41) PTGS1GSTK1GLO1MEN1KMT2A
SCHEMBL8436887 0.98 PTGS1 (0.41) PTGS1GSTK1GLO1MEN1KMT2A
SCHEMBL8213852 0.98 PTGS1 (0.41) PTGS1GSTK1GLO1MEN1KMT2A
SCHEMBL6130183 0.98 PTGS1 (0.41) PTGS1GSTK1GLO1MEN1KMT2A
SCHEMBL8214832 0.98 PTGS1 (0.41) PTGS1GSTK1GLO1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1455 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070081979-A1 Multi-functional chimeric hematopoietic receptor agonists MC KEARN JOHN P 2007-04-12 US claimed
EP-1337643-A4 MANIPULATION OF PLANT LIFE CYCLES AND/OR GROWTH PHASES MOLECULAR PLANT BREEDING NOMINEES LTD (AU) 2005-08-10 EP claimed
EP-1313504-A4 METHODS AND COMPOSITIONS FOR INHIBITING ANGIOGENESIS PHILADELPHIA HEALTH & EDUCATIO (US) 2004-06-30 EP claimed
WO-2004007527-A2 SECRETED PROTEINS INCYTE CORPORATION (US) 2004-01-22 WO claimed
EP-1337643-A1 MANIPULATION OF PLANT LIFE CYCLES AND/OR GROWTH PHASES Molecular Plant Breeding Nominees Ltd (AU) 2003-08-27 EP claimed
EP-1313504-A2 METHODS AND COMPOSITIONS FOR INHIBITING ANGIOGENESIS Philadelphia, Health and Education Corporation (US) 2003-05-28 EP claimed
WO-2002038768-A1 MANIPULATION OF PLANT LIFE CYCLES AND/OR GROWTH PHASES MOLECULAR PLANT BREEDING NOMINEES LTD (AU) 2002-05-16 WO claimed
WO-2002017857-A2 METHODS AND COMPOSITIONS FOR INHIBITING ANGIOGENESIS PHILADELPHIA, HEALTH AND EDUCATION CORPORATION (US) 2002-03-07 WO claimed
US-5763254-A ENDOGENOUS TO STRAIN OF FUNGUS OTHER THAN TRICHODERMA OR PHANEROCHAETE NOVO NORDISK A/S (DK) 1998-06-09 US claimed
EP-0829538-A2 Peptidoglycan recognition proteins and their production WAKO PURE CHEMICAL INDUSTRIES, LTD (JP) 1998-03-18 EP claimed
CN-1035886-C Dye Transfer inhibiting compositions PROCTER & GAMBLE (US) 1997-09-17 CN claimed
CN-1034084-C Compact detergent compositions with high activity cellulase PROCTER & GAMBLE (US) 1997-02-19 CN claimed
US-5457046-A Polypeptides NOVO NORDISK A/S (DK) 1995-10-10 US claimed
EP-0531315-A1 AN ENZYME CAPABLE OF DEGRADING CELLULOSE OR HEMICELLULOSE. NOVO NORDISK AS (DK) 1993-03-17 EP claimed
WO-1991017244-A1 AN ENZYME CAPABLE OF DEGRADING CELLULOSE OR HEMICELLULOSE NOVO NORDISK A/S (DK) 1991-11-14 WO claimed
US-4740585-A OLIGOPEPTIDES THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 1988-04-26 US claimed
US-4736017-A FROM PURIFIED GAL-GAL PILUS PROTEINS OR FRAGMENTS THERE OF THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 1988-04-05 US claimed
CN-114829610-B Method for improving photosynthetic organisms 农牧研究公司 2024-07-16 CN disclosed
WO-1991017243-A1 A CELLULASE PREPARATION COMPRISING AN ENDOGLUCANASE ENZYME NOVO NORDISK A/S (DK) 1991-11-14 WO disclosed
WO-1991017244-A1 AN ENZYME CAPABLE OF DEGRADING CELLULOSE OR HEMICELLULOSE NOVO NORDISK A/S (DK) 1991-11-14 WO disclosed