Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 4/20 | 0.80 |
| ▸ | DRD4 | P21917 | 2/20 | 0.80 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7996960 | 0.99 | HTR2A (0.79) | HTR2ADRD4MAPTDRD2HTR1A | |
| SCHEMBL7679404 | 0.89 | DRD4 (1.00) | HTR2ADRD4MAPT | |
| SCHEMBL9298366 | 0.88 | HTR2A (0.81) | HTR2ADRD4MAPTDRD2HTR1A | |
| Hydrochloric Acid SCHEMBL7990183 | 0.88 | HTR2A (0.80) | HTR2ADRD4MAPTDRD2HTR1A | |
| SCHEMBL7979523 | 0.83 | HTR2A (0.56) | HTR2ADRD4DRD2HTR7 | |
| Hydrochloric Acid SCHEMBL7993019 | 0.82 | DRD4 (0.55) | HTR2ADRD4 | |
| SCHEMBL9597561 | 0.81 | HTR2A (0.69) | HTR2ADRD4DRD2HTR1A | |
| SCHEMBL9411187 | 0.78 | HTR2A (0.64) | HTR2ADRD4DRD2HTR1A | |
| Hydrochloric Acid SCHEMBL9411098 | 0.77 | HTR2A (0.63) | HTR2ADRD4DRD2 | |
| Hydrochloric Acid SCHEMBL9666450 | 0.76 | HTR2A (0.49) | HTR2ADRD4MAPTDRD2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4933453-A | ANTIPSYCHOTIC, ANALGESIC, ANTICONVULSANT, AND ANXIOLYTIC AGENTS | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1990-06-12 | — | — | US | claimed |
| US-6284775-B1 | PSYCHOLOGICAL DISORDERS | AVENTIS PHARMACEUTICALS INC. | 2001-09-04 | — | — | US | disclosed |
| US-5801186-A | ANTIPSYCHOTIC AGENTS | HOECHST MARION ROUSSEL, INC. (US) | 1998-09-01 | — | — | US | disclosed |
| US-5371087-A | Antipsychotic, analgesics, anticonvulsant and anxiolytic agent | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1994-12-06 | — | — | US | disclosed |
| US-5229388-A | 3-[4-(1-substituted-4-piperazinyl)butyl]-4-thiazolidinone and related compounds | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1993-07-20 | — | — | US | disclosed |
| US-5136037-A | 3-(4-substituted-4-piperazinyl)butyl-4-thiazolidinone and related compounds | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1992-08-04 | — | — | US | disclosed |
| US-5037984-A | Anticonvulsants; anxiolytic agents | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1991-08-06 | — | — | US | disclosed |
| US-4933453-A | ANTIPSYCHOTIC, ANALGESIC, ANTICONVULSANT, AND ANXIOLYTIC AGENTS | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1990-06-12 | — | — | US | disclosed |