Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.81 |
| ▸ | DRD4 | P21917 | 2/20 | 0.81 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 2/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7990183 | 0.99 | HTR2A (0.80) | HTR2ADRD4MAPTHTR1AADRA1A | |
| SCHEMBL7997143 | 0.88 | HTR2A (0.80) | HTR2ADRD4MAPTHTR1ADRD2 | |
| Hydrochloric Acid SCHEMBL7996960 | 0.88 | HTR2A (0.79) | HTR2ADRD4MAPTHTR1ADRD2 | |
| Maleic Acid SCHEMBL7979544 | 0.84 | DRD4 (0.88) | HTR2ADRD4MAPTADRA1A | |
| Fumaric Acid SCHEMBL7979548 | 0.84 | DRD4 (0.88) | HTR2ADRD4MAPTADRA1A | |
| SCHEMBL7679404 | 0.78 | DRD4 (1.00) | HTR2ADRD4MAPTADRA1A | |
| SCHEMBL7996802 | 0.74 | HTR2A (0.73) | HTR2ADRD4MAPTHTR1AADRA1A | |
| Hydrochloric Acid SCHEMBL9666450 | 0.73 | HTR2A (0.49) | HTR2ADRD4MAPTHTR1ADRD2 | |
| SCHEMBL7990238 | 0.72 | LMNA (0.58) | HTR1AADRA1A | |
| SCHEMBL7993315 | 0.72 | DRD4 (0.56) | HTR2ADRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4933453-A | ANTIPSYCHOTIC, ANALGESIC, ANTICONVULSANT, AND ANXIOLYTIC AGENTS | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1990-06-12 | — | — | US | claimed |
| US-5371087-A | Antipsychotic, analgesics, anticonvulsant and anxiolytic agent | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1994-12-06 | — | — | US | disclosed |
| US-5229388-A | 3-[4-(1-substituted-4-piperazinyl)butyl]-4-thiazolidinone and related compounds | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1993-07-20 | — | — | US | disclosed |
| US-5136037-A | 3-(4-substituted-4-piperazinyl)butyl-4-thiazolidinone and related compounds | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1992-08-04 | — | — | US | disclosed |
| US-5037984-A | Anticonvulsants; anxiolytic agents | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1991-08-06 | — | — | US | disclosed |
| US-4933453-A | ANTIPSYCHOTIC, ANALGESIC, ANTICONVULSANT, AND ANXIOLYTIC AGENTS | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1990-06-12 | — | — | US | disclosed |