Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 2/20 | 0.48 |
| ▸ | KCNK3 | O14649 | 3/20 | 0.47 |
| ▸ | KCNK9 | Q9NPC2 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | FNTA | P49354 | 6/20 | 0.45 |
| ▸ | FNTB | P49356 | 6/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | PGGT1B | P53609 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7997160 | 1.00 | F2R (0.48) | F2RKCNK3KCNK9ALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8868833 | 0.99 | F2R (0.47) | F2RKCNK3KCNK9ALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8868826 | 0.99 | F2R (0.47) | F2RKCNK3KCNK9ALDH1A1SMN1; SMN2 | |
| SCHEMBL8000410 | 0.81 | NPC1 (0.45) | FNTAFNTBPGGT1B | |
| SCHEMBL8000412 | 0.81 | NPC1 (0.45) | FNTAFNTBPGGT1B | |
| Hydrochloric Acid SCHEMBL8870297 | 0.80 | NPC1 (0.44) | FNTAFNTBPGGT1B | |
| Hydrochloric Acid SCHEMBL8870302 | 0.80 | NPC1 (0.44) | FNTAFNTBPGGT1B | |
| SCHEMBL7995119 | 0.80 | FNTA (0.48) | SMN1; SMN2FNTAFNTBKMT2APGGT1B | |
| SCHEMBL7993171 | 0.80 | FNTA (0.48) | SMN1; SMN2FNTAFNTBKMT2APGGT1B | |
| SCHEMBL7993175 | 0.80 | FNTA (0.48) | SMN1; SMN2FNTAFNTBKMT2APGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996030014-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1996-10-03 | — | — | WO | claimed |
| EP-0817629-A4 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO INC (US) | 2000-03-08 | — | — | EP | disclosed |
| EP-0817629-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | Merck & Co., Inc. (US) | 1998-01-14 | — | — | EP | disclosed |
| US-5631280-A | Inhibitors of farnesyl-protein transferase | MERCK & CO., INC. (US) | 1997-05-20 | — | — | US | disclosed |
| WO-1996030014-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1996-10-03 | — | — | WO | disclosed |